D. On the inner surface of the plasma membrane. A. Lipid-soluble hormone receptors are located inside the plasma membrane and easily diffuse across the plasma membrane to bind to either cytosolic or nuclear receptors.
Thyrotropin-releasing hormone (TRH) from the hypothalamus stimulates TSH secretion from the anterior pituitary. Secretion of TSH stimulates the synthesis and secretion of THs. Increasing levels of T4 and triiodothyronine (T3) then generate negative feedback on the pituitary and hypothalamus to inhibit TRH and TSH synthesis. ...
Prolactin-releasing factor targets the anterior pituitary gland to stimulate the secretion of prolactin.
ADH was originally named vasopressin because, in extremely high doses, it causes vasoconstriction and a resulting increase in arterial blood pressure. However, significant vasoconstriction may only be achieved pharmacologically.
Ca++ is considered an important second messenger that facilitates the binding of a hormone (e.g., norepinephrine, angiotensin II) to a surface receptor, activating the enzyme phospholipase C through a G protein inside the plasma membrane. The control of calcium in cells is important because it: A.
Peptide or protein hormones, such as insulin, pituitary, hypothalamic, and parathyroid, are water soluble and circulate in free (unbound) forms. When insulin binds its receptors on muscle cells, an increase in glucose uptake by the muscle cells is the result.
Cortisol and adrenal androgens are lipid-soluble hormones and are primarily bound to a carrier or transport protein in circulation. Most protein hormones are transported in the bloodstream and are: A. Bound to a lipid-soluble carrier. B. Free in an unbound, water-soluble form.