where is the inactive form of vitamin d converted to the active form course hero

by Meta Lockman 7 min read

What is the pathophysiology of vitamin A and vitamin D deficiency?

May 22, 2015 · Where is the inactive form of vitamin D converted to the active form? A. in the skin B. in the liver and then kidneys C. in the stomach and small intestine D. in the pancreas and gallbladder ANS: B B )

Why is vitamin D hydroxylated in the liver and kidney?

Mar 23, 2021 · Correct! It is the inactive form of vitamin D taken in through the skin via UV rays It is the inactive form of synthetic vitamin D It is the active form of vitamin D, converted in the liver It is the active form of vitamin D, converted in the kidney Question 10 2.5 / 2.5 pts A patient is said to be in stage 4 kidney disease.

What is the RDA for vitamin D and vitamin C?

Question: and then the convert it to its active form 1. For the body to use inactive Vitamin D from sunlight or the diet, the parathyroid gland; kidneys liver; kidneys liver; parathyroid gland kidneys; liver 2. Seth has a family history of skin cancer and avoids direct sunlight. To prevent vitamin D deficiency, Seth should increase his intake ...

Where is vitamin A converted to beta-carotene B?

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Where is the in active form of vitamin D converted to the active form?

The first hydroxylation, which occurs in the liver, converts vitamin D to 25-hydroxyvitamin D [25(OH)D], also known as "calcidiol." The second hydroxylation occurs primarily in the kidney and forms the physiologically active 1,25-dihydroxyvitamin D [1,25(OH)2D], also known as "calcitriol" [1].Apr 28, 2022

Where is inactive vitamin D formed?

Vitamin D, in either the D2 or D3 form, is considered biologically inactive until it undergoes two enzymatic hydroxylation reactions. The first takes place in the liver, mediated by the 25-hydroxylase (most likely cytochrome P450 2R1 [CYP2R1]) which forms 25-hydroxyvitamin D (hereafter referred to as 25OHD).

How does vitamin D become active?

The sun's energy turns a chemical in your skin into vitamin D3, which is carried to your liver and then your kidneys to transform it to active vitamin D. The first stop is in the liver, where vitamin D picks up extra oxygen and hydrogen molecules to become 25-hydroxyvitamin D, or 25(OH)D.

What is the active form of vitamin D called?

The liver and kidneys convert vitamin D (produced in the skin and taken up in the diet), into the active hormone, which is called calcitriol.

Is the active form of vitamin D quizlet?

Calcitriol is the most physiologically active form of vitamin D in the body.

Is vitamin D3 active?

Vitamin D, as either D3 or D2, does not have significant biological activity. Rather, it must be metabolized within the body to the hormonally-active form known as 1,25-dihydroxycholecalciferol.

Is calcitriol the active form of vitamin D?

Calcitriol is the active form of vitamin D, and it is essential for calcium absorption and bone mineralization.

Which form of vitamin D is best?

In supplements, two forms of vitamin D are available: D2, which is called ergocalciferol, and D3, which is called cholecalciferol. Both are effective, but D3 seems to be more effective at higher dosages.

What is vitamin (1)?

A vitamin (1) is a lack or shortage of a particular vitamin, and prolonged insufficiency can eventually lead to a (2), characterized by harmful symptoms.

What are the functions of vitamins?

A vitamin is an organic compound that must be obtained from the diet and is needed to sustain life. Vitamins have many functions throughout the body. For example, vitamins C & E, function as antioxidants, the B vitamins function as coenzymes, and vitamin D is important for calcium regulation. A vitamin deficiency is a lack or shortage of a particular vitamin, and prolonged insufficiency can eventually lead to a vitamin deficiency disease, characterized by harmful symptoms. Both vitamins and minerals are nutrients required in small amounts to sustain life. Vitamins are organic compounds that cannot be synthesized in the body and therefore must be obtained from the diet. Different vitamins perform various functions throughout the body. Vitamins C and E are two nutrients involved in antioxidant functions, the B vitamins function as coenzymes for energy metabolism, and vitamin D is a hormone required for the regulation of calcium in the blood. A vitamin deficiency disease is a disease that is directly caused by inadequate concentrations of a particular nutrient. When the body is deficient in a vitamin, the function associated with that vitamin is impaired. A vitamin deficiency disease is a disease that is directly caused by inadequate concentrations of a particular nutrient. The diseases are generally reversible once the person begins consuming adequate levels of the nutrient. A primary deficiency is caused by inadequate intake of a particular vitamin, whereas a secondary deficiency is caused by an underlying problem, such as the inability to absorb a vitamin. The deficiency disease associated with inadequate intake of vitamin D is loss of bone mass. In children, this is called rickets, which results in inadequate mineralization of the skeleton. The elderly population is at a greater risk for vitamin D deficiency due to due to insufficient vitamin D intake, low sunlight exposure, and changes that occur during aging that interfere with vitamin D synthesis and metabolism in the cells (for example, the skin and kidneys lose some capacity to synthesize vitamin D).The conversion of inactive vitamin D to calcidiol occurs in the liver before then being converted to the active form of vitamin D, termed calcitriol, in the kidneys. In order for this conversion to occur, the inactive form of vitamin D must be obtained from dietary sources or from skin exposure to ultraviolet sunlight. Therefore, a situation where your liver is not functioning properly, such as in the case of liver disease, as well as risk factors for decreased sun exposure, such as living in a region without sunlight, would increase your risk of deficiency. The activation of vitamin D is required to increase blood calcium levels, resulting in adequate bone mineralization. Vitamin D activation leads to increased absorption of calcium in the small intestine, which would decrease the risk of inadequate bone mineralization. A primary deficiency disease is a direct result of not taking in enough of a particular nutrient, such as vitamin D, and would not occur with adequate intake. In the case of vitamin D, the primary deficiency is an inability to mineralize bone, resulting in rickets or osteomalacia. A secondary deficiency disease may be associated with decreased intake and is likely due to an underlying disorder that limits the body's ability to use the vitamin.A vitamin is an organic compound that must be obtained from the diet and is needed to sustain life. Vitamins have many functions throughout the body. For example, vitamin A is important for vision, vitamin C is important for collagen synthesis, and vitamin D is important for calcium regulation. A vitamin deficiency is a lack or shortage of a particular vitamin, and prolonged insufficiency can eventually lead to a vitamin deficiency disease, characterized by harmful symptoms. Both vitamins and minerals are nutrients required in small amounts to sustain life. Vitamins are organic compounds that cannot be synthesized in the body and therefore must be obtained from the diet. Different vitamins perform various functions throughout the body. Vitamin A is an important vitamin involved with vision and preventing night blindness, vitamin C is important for collagen synthesis, and vitamin D is a hormone required for the regulation of calcium in the blood. A vitamin deficiency disease is a disease that is directly caused by inadequate concentrations of a particular nutrient. When the body is deficient in a vitamin, the function associated with that vitamin is impaired.A vitamin deficiency disease is a disease that is directly caused by inadequate concentrations of a particular nutrient. The diseases are generally reversible once the person begins consuming adequate levels of the nutrient. A primary deficiency is caused by inadequate intake of a particular vitamin, whereas a secondary deficiency is caused by an underlying problem, such as the inability to absorb a vitamin. The deficiency disease associated with inadequate intake of vitamin D is loss of bone mass. In adults, this is called osteomalacia, which is often characterized by a severe pain in the bones and joints.A major source of vitamin D is synthesized in the body when ultraviolet B photons (UVB) from the sun are absorbed by 7-dehydrocholesterol in the skin, leading to the eventual conversion to the active form of vitamin D. Pigmentation reduces this production in the skin. Therefore, darker-skinned individuals will experience slower vitamin D synthesis than lighter-skinned individuals.When the ultraviolet rays of the sun hit your skin, they are absorbed and react to form the inactive form of vitamin D, known as Provitamin D3. In order for this conversion to occur, the inactive form of vitamin D must be obtained from dietary sources or from skin exposure to ultraviolet sunlight and then be converted to calcidiol in the liver. From there, calcidiol is further converted to the active form of vitamin D, termed calcitriol, in the kidneys. Therefore, a situation where your kidneys are not functioning properly, such as in the case of kidney disease, as well as risk factors for decreased sun exposure, such as living in a region with little sun, would increase your risk of deficiency. The activation of vitamin D is required to increase blood calcium levels, resulting in adequate bone mineralization. Vitamin D activation leads to increased absorption of calcium in the kidneys, which decreases the risk of inadequate bone mineralization.A primary deficiency disease is a direct result of not taking in enough of a particular nutrient, such as vitamin D, and would not occur with adequate intake. In the case of vitamin D, the primary deficiency is an inability to mineralize bone, resulting in rickets or osteomalacia. A secondary deficiency disease may be associated with decreased intake and is likely due to an underlying disorder that limits the body's ability to use the vitamin.A vitamin is an organic compound that must be obtained from the diet and is needed to sustain life. Vitamins have many functions throughout the body. For example, vitamins C and E function as antioxidants, the B vitamins function as coenzymes, and vitamin D is important for calcium regulation. A vitamin deficiency is a lack or shortage of a particular vitamin, and prolonged insufficiency can eventually lead to a vitamin deficiency disease, characterized by harmful symptoms. Both vitamins and minerals are nutrients required in small amounts to sustain life. Vitamins are organic compounds that cannot be synthesized in the body and therefore must be obtained from the diet. Different vitamins perform various functions throughout the body. Vitamins C and E are two nutrients involved in antioxidant functions, the B vitamins function as coenzymes for energy metabolism, and vitamin D is a hormone required for the regulation of calcium in the blood. A vitamin deficiency disease is a disease that is directly caused by inadequate concentrations of a particular nutrient. When the body is deficient in a vitamin, the function associated with that vitamin is impaired.A vitamin deficiency disease is a disease that is directly caused by inadequate concentrations of a particular nutrient. The diseases are generally reversible once the person begins consuming adequate levels of the nutrient. A primary deficiency is caused by inadequate intake of a particular vitamin, whereas a secondary deficiency is caused by an underlying problem, such as the inability to absorb a vitamin. The deficiency disease associated with inadequate intake of vitamin D is loss of bone mass. In adults, this is called osteomalacia, which is often characterized by severe pain in the bones and joints. Adequate vitamin D levels play a role in hyperparathyroidism by maintaining calcium levels; however, the disease is not directly caused by a vitamin D deficiency and vitamin D itself cannot cure the disease. Therefore, it is not a vitamin D deficiency disease.A major source of vitamin D is synthesized in the body when ultraviolet B photons (UVB) from the sun are absorbed by 7-dehydrocholesterol in the skin, leading to the eventual conversion to the active form of vitamin D. Therefore, individuals who spend more time outdoors and are exposed to the sun will generally be less deficient in vitamin D.The active, usable form of vitamin D is termed calcitriol. It is produced following the conversion from calcidiol in the kidneys. In order for this conversion to occur, the inactive form of vitamin D must be obtained from dietary sources or from skin exposure to ultraviolet sunlight. Therefore, a situation where your kidneys are not functioning properly, such as in the case of kidney disease, as well as risk factors for decreased sun exposure, such as wearing protective clothing, would increase your risk of vitamin D deficiency. The activation of vitamin D is required to increase blood calcium levels, resulting in adequate bone mineralization. Decreased vitamin D activation leads to decreased absorption of calcium in the small intestine, which would increase the risk of inadequate bone mineralization.A primary deficiency disease is a direct result of not taking in enough of a particular nutrient, such as vitamin D, and would not occur with adequate intake. In the case of vitamin D, the primary deficiency is an inability to mineralize bone, resulting in rickets or osteomalacia. A secondary deficiency disease may be associated with decreased intake and is likely due to an underlying disorder that limits the body's ability to use the vitamin.

What are some examples of vitamins?

Vitamins have many functions throughout the body. For example, vitamins C and E function as (1), the B vitamins function as (2), and vitamin D is important for (3).

What is the purpose of vitamin?

Vitamins are organic compounds that are vital to life and required for normal function and maintenance in the body. Vitamin nutrition is associated with many conditions and disorders, although it is important to note that the only disease a vitamin can cure is the one caused by a deficiency of that vitamin.

Does vitamin D cause osteomalacia?

Vitamin D has many functions throughout the body. While severe deficiency directly leads to poor bone mineralization, resulting in rickets and osteomalacia, current research suggests that a deficit in vitamin D may be involved in the etiology of many disorders, including cardiovascular disease, respiratory infection, diabetes, infectious disease, and some cancers.

Does vitamin D increase calcium absorption?

Increased activation of vitamin D will result in increased absorption of calcium in the small intestine and decreased risk of inadequate bone mineralization.

Is Marie deficient in vitamin D?

Lately, she has had terrible bone and joint pain and a recent checkup confirms that Marie is deficient in vitamin D and has a disease called (1), or poor bone mineralization. This would be considered a (2) deficiency that (3) be directly treated with vitamin D supplementation.