Histamine in the stomach occurs in endocrine cells (so-called enterochromaffin-like (ECL) cells), mast cells, and neurons. The ECL cells are peptide hormone-producing cells. In mommals they are located basally in the oxyntic gland area, in the chief-cell-rich region. Parietal cells predominate in the mid-region.
Four major types of secretory epithelial cells cover the surface of the stomach and extend down into gastric pits and glands:Mucous cells: secrete an alkaline mucus that protects the epithelium against shear stress and acid.Parietal cells: secrete hydrochloric acid.Chief cells: secrete pepsin, a proteolytic enzyme.More items...
We were surprised to find that histamine, HDC, and VMAT1 were all present in G cells. Our results suggest that G cells synthesize and secrete gastrin and histamine.
G-cells secrete gastrin into the systemic circulation, which allows the delivery of gastrin to parietal cells and enterochromaffin-like (ECL) cells in the gastric fundus and cardiac. Gastrin stimulates the proliferation of gastric mucosal endocrine cells (parietal cells, ECL cells).Mar 6, 2021
Gastric chief cells secrete pepsin as an inactive zymogen called pepsinogen. Parietal cells within the stomach lining secrete hydrochloric acid that lowers the pH of the stomach.May 9, 2021
Gastric chief cells produce pepsinogen, which is activated by the acid to form pepsin. Pepsin is a protease that can digest and damage stomach cells. To prevent these disastrous effects, mucus and bicarbonate ions (HCO3−) are secreted by the foveolar cells.
Delta cells (δ-cells or D cells) are somatostatin-producing cells. They can be found in the stomach, intestine and the pancreatic islets....Delta cellControl of stomach acidDetailsLocationstomach, intestine and the pancreatic isletsFunctionSomatostatin production4 more rows
Parietal cells (also called oxyntic cells) are the stomach epithelium cells which secrete gastric acid.
Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas.
serotoninThe argentaffin cells are granular cells that secretes serotonin which is responsible for the peristaltic movement of the muscles of the digestive tract.
S cells are cells which release secretin, found in the jejunum and duodenum. They are stimulated by a drop in pH to 4 or below in the small intestine's lumen.
pyloric endgastrin, any of a group of digestive hormones secreted by the wall of the pyloric end of the stomach (the area where the stomach joins the small intestine) of mammals. In humans, gastrin occurs in three forms: as a 14-, 17-, and 34-amino-acid polypeptide.