what is a diseases clinical course

The course of a disease, also called its natural history, refers to the development of the disease in a patient, including the sequence and speed of the stages and forms they take. Typical courses of diseases include: chronic; recurrent or relapsing; subacute: somewhere between an acute and a chronic course

Full Answer

What is the meaning of disease course?

DISEASE COURSE. The process of a pathological condition from inception to resolution. DISEASE COURSE: "The disease course starts with its inception and runs till it is gone.".

When does a subclinical disease become a clinical disease?

Often, subclinical diseases will become clinical diseases in time. Subclinical diseases are conditions where the disease is identifiable with laboratory testing or imaging but have no outward signs or symptoms.

What is a course of medication?

A course of medication is a period of continual treatment with drugs, sometimes with variable dosage and in particular combinations. For instance treatment with some drugs should not end abruptly. Instead, their course should end with a tapering dosage.

What is a precursor to a disease?

A precursor is a sign or event that precedes the course or a particular stage in the course of a disease, for example chills often are precursors to fevers. ^ Ray M. Merrill (2013).

What is a clinical disease?

Clinical disease is what your aunt was experiencing. It is having the full disease condition, often with a variety of symptoms, after the disease has progressed past the initial stages. At this stage it will cause signs and symptoms that may provide clues as to the cause of the condition.

What are subclinical screening programs?

Screening programs are designed to identify subclinical conditions before they become problematic. This allows for early treatment and, hopefully, limited damage to the body. Hypothyroidism and diabetes are both examples of conditions with subclinical and clinical disease states.

When diabetes is diagnosed early, what can be initiated?

When diabetes is diagnosed early, medical and diet therapy can be initiated to prevent damage to the body and prevent the patient from feeling ill. Lesson Summary. Medical conditions can exist as either subclinical diseases or clinical diseases. Often, subclinical diseases will become clinical diseases in time.

Is chlamydia a clinical infection?

Chlamydia. Infections can be sub clinical or clinical. For example, if a young man goes to a Sexually Transmitted Infections clinic because he is experiencing pain when he urinates, and is diagnosed with chlamydia (a very common sexually transmitted infection), he would have a clinical infection. On the other hand, an example ...

Do primary care providers screen for diabetes?

However, primary care providers will frequently screen for diabetes at a regular interval in the hopes of finding the condition in a subclinical state.

Is a subclinical infection contagious?

Infections can also exist in a subclinical and clinical state. However, it is important to remember that individuals are often contagious even if they feel well.

What is progressive MS?

Multiple sclerosis is a chronic, progressive disease that leads to increasing disability in many individuals. Approximately 85 percent of individuals initially present with a relapsing-remitting course of the disease ( Lublin et al., 2013 ). Most people with relapsing remitting MS transition to a more progressive course called secondary-progressive MS (SPMS) that is characterized by accumulation of disability with fewer relapses. About 10 to 15 percent of people with MS begin the disease with a progressive course, without relapses, known as primary progressive MS (PPMS).#N#In 2013, the International Advisory Committee on Clinical Trials of MS identified four MS disease courses ( Lublin et al., 2013). In 2020 this group further clarified the concepts underlying these disease courses, highlighting the need for time framing the disease course modifiers “activity” and “progression” ( Lublin et al., 2020 ). The Committee also clarified the terms “worsening” and “progression” and provided guidance for their use.

Is RIS a course of MS?

Although not considered a course of MS, radiologically isolated syndrome (RIS) has been used to describe asymptomatic individuals who have MRI clinical features that are suggestive of MS and are therefore at an increased risk of developing MS ( Okuda et al., 2009 ).

What is the course of a disease?

The course of a disease, also called its natural history, refers to the development of the disease in a patient, including the sequence and speed of the stages and forms they take. Typical courses of diseases include: chronic. recurrent or relapsing.

What does "course" mean in medicine?

In medicine the term course generally takes one of two meanings, both reflecting the sense of " path that something or someone moves along...process or sequence or steps ": A course of medication is a period of continual treatment with drugs, ...

What is course of medication?

A course of medication is a period of continual treatment with drugs, sometimes with variable dosage and in particular combinations. For instance treatment with some drugs should not end abruptly. Instead, their course should end with a tapering dosage.

What is precursor in medical terms?

A precursor is a sign or event that precedes the course or a particular stage in the course of a disease, for example chills often are precursors to fevers.

What does "acute" mean?

recurrent or relapsing. subacute: somewhere between an acute and a chronic course. acute: beginning abruptly, intensifying rapidly, not lasting long. fulminant or peracute: particularly acute, especially if unusually violent.

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Abstract

We evaluated the clinical course of asymptomatic and mildly symptomatic patients with laboratory-confirmed coronavirus disease (COVID-19) admitted to community treatment centers (CTCs) for isolation in South Korea.

Materials and Methods

All patients included in the study tested positive for SARS-CoV-2 by rRT-PCR analysis of oral or nasal swab samples ( 13 ). After diagnosis, patients were isolated at home, and volunteer doctors interviewed patients through telephone calls > 2 times a day. The volunteer doctors also performed risk assessment and patient classifications.

Results

Among 640 patients treated at 2 CTCs, we excluded 8 from our analysis, 7 because we did not have enough data, and 1 because the patient was transferred from the hospital and discharged soon after symptom improvement. We analyzed data on 632 patients, 272 from CTC1 and 360 from CTC2.

Discussion

We investigated the clinical characteristics and outcomes COVID-19 cases in asymptomatic and mildly symptomatic patients admitted for isolation and monitoring in 2 CTCs in South Korea. The mean duration from diagnosis to virologic remission was 20.1 days.

Acknowledgments

We thank the city of Daegu, Kyungpook National University, Kyungpook National University Hospital, Daegu National Education Training Institute, Daegu Medical Association, and Daegu Center for Infectious Disease Control and Prevention for assistance in fighting COVID-19.