what are the characteristics of a good solid support in gas chromatography course hero

by Alessia Trantow 7 min read

What is gas solid chromatography (GSC)?

David S. Hage, in Principles and Applications of Clinical Mass Spectrometry, 2018 Gas-Solid Chromatography. GSC is a type of GC in which the same material acts as both the stationary phase and the support. 7 In this method, chemicals are retained by their adsorption to the surface of the support. This support is often an inorganic material such as silica or alumina.

What is meant by gas chromatography?

Characteristics Of Gas Chromatography. Gas chromatography is analytical technique used to separate and analyze the compounds which can be directly vaporized, without decomposition. Gas chromatography is utilized to purify, separate and identify a compound in a mixture. Gas Chromatography (GC) can be used to synthesize and extract pure ...

What is the history of gas solid chromatography?

Gas Chromatography Types of Gas Chromatography i) gas-liquid chromatography (GLC) widespread use in all fields of science where its name is usually shortened to gas chromatography (GC). ii) gas-solid chromatography (GSC). has limited application because of semi permanent retention of active or polar molecules and severe tailing of elution peaks.

What are gas chromatography columns made of?

Nov 16, 2021 · Solid Support Materials The solid support should ideally have the following properties: 1. Large surface area (at least 1 m 2 /g) 2. Has a good mechanical stability 3. Thermally stable 4. Inert surface in order to simplify retention behavior and prevent solute adsorption 5. Has a particle size in the range from 100-400 m m

What is gas chromatography?

Gas chromatography is analytical technique used to separate and analyze the compounds which can be directly vaporized, without decomposition. Gas chromatography is utilized to purify, separate and identify a compound in a mixture. Gas Chromatography (GC) can be used to synthesize and extract pure components from a mixture of compounds.

What is the difference between gas chromatography and gas chromatography?

Chromatography means of separating and tentatively identifying the components of a mixture. Gas chromatography separates mixtures on the basis of their distribution between a stationary liquid phase and a mobile has phase. In GC, the moving phase is actually a gas called carrier gas, which flows through a column.

Why is mole ratio important?

Mole ratio is considered a conversion factor since it helps to convert units with the use of moles. It is used in stoichiometry and other calculations and comes out of the balanced chemical equations. Stoichiometry is the measurement of elements that concerns the chemical quantities produced or taken in a reaction.

How to use turbidimetric and chromogenic methods?

Both the turbidimetric and the chromogenic methods can be used as quantitative kinetic methods simply by plotting standard curves of time vs endotoxin concentration. Spectrophotometric instruments can be used to detect changes in colour and turbidity at much lower concentration than that need to form a visible gel-clot. Doing this makes the turbidimetric and chromogenic methods much more sensitive that the gel-clot method. The sensitivity in this case is determined by the lowest concentration that is on the standard

What is a GC?

GC is also termed as VPC (Vapor-Phase Chromatography) or GLPC ( Gas –Liquid Partition Chromatography). The mobile phase in GC is usually a carrier gas, which may be helium (an inert gas) or nitrogen (an unreactive gas). A thin liquid or polymer layer supported on an unreactive solid is used as stationary phase.

What is stationary phase?

A thin liquid or polymer layer supported on an unreactive solid is used as stationary phase. It is walled in a column of glass or metal. "Gas separator" or "Aerograph" are other terms of Gas Chromatograph. Retention time of different components vary according to their interaction with the coating of column walls.

What is stoichiometry in chemical reactions?

Stoichiometry is the measurement of elements that concerns the chemical quantities produced or taken in a reaction. The process of relating the mass and mole quantities of reactants or products in a reaction. It uses a balanced chemical equation, mole ratio, and sometimes needs mole mass. Read More.