Table 1: Medicines associated with priapismMedicine classExamplesAntipsychotics & Antidepressantsrisperidone, olanzapine, clozapine, chlorpromazine, quetiapine, sertraline, citalopram, escitalopram, lithium, fluoxetine, trifluoperazine, pericyazineVasoactive erectile agentsalprostadil, papaverine8 more rows•Sep 5, 2014
Priapism is a persistent, usually painful, erection that lasts for more than four hours and occurs without sexual stimulation. The condition develops when blood in the penis becomes trapped and is unable to drain. If the condition is not treated immediately, it can lead to scarring and permanent erectile dysfunction.
Investigators have suggested that the mechanism of trazodone-induced priapism is through its α-adrenergic blocking activity. Trazodone has also been reported to induce priapism of the clitoris in women.
Ischemic priapism is considered a medical emergency and requires immediate treatment. If left untreated, the condition can significantly damage erectile function, by causing extensive scar tissue build-up and impotence. Non-ischemic Priapism This type of priapism is not as common or painful.
The condition is caused by trauma to a branch of the cavernosal artery, resulting in a greater arterial inflow to the corpora cavernosa than the venous channels can drain. This rare form of priapism is typically painless because there is no tissue ischaemia.
Drugs that may cause erection problemsAmitriptyline (Elavil)Amoxapine (Asendin)Buspirone (Buspar)Chlordiazepoxide (Librium)Chlorpromazine (Thorazine)Clomipramine (Anafranil)Clorazepate (Tranxene)Desipramine (Norpramin)More items...•
Nausea, vomiting, diarrhea, drowsiness, dizziness, tiredness, blurred vision, changes in weight, headache, muscle ache/pain, dry mouth, bad taste in the mouth, stuffy nose, constipation, or change in sexual interest/ability may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Trazodone is in a class of medications called serotonin modulators.
Psychotropic medications can also cause priapism, including the psychotropic agents trazodone, thioridazine, and chlorpromazine. These medications are associated with a small but definite risk of priapism.
The most common cause of high-flow priapism, regardless of age, is arteriovenous fistula formation secondary to perineal trauma, most commonly straddle-type injuries.
The re-occurring, painful erections usually last between 2 and 3 hours before returning to a flaccid (soft or limp) state. If you have this type of priapism, it may occur during sleep, or before or after sexual stimulation. Over time, the episodes of priapism may become more frequent and last longer.
Physical issues like heart disease, high cholesterol, high blood pressure, diabetes, obesity, and smoking can all cause erectile dysfunction. On the other hand, depression, anxieties, stress, relationship problems, and other mental health concerns can also interfere with sexual feelings.
The re-occurring, painful erections usually last between 2 and 3 hours before returning to a flaccid (soft or limp) state. If you have this type of priapism, it may occur during sleep, or before or after sexual stimulation. Over time, the episodes of priapism may become more frequent and last longer.
A penile erection can normally last anywhere from a few minutes to about half an hour. On average, men have five erections a night while they're sleeping, each lasting about 25 to 35 minutes (Youn, 2017).
11 erectionsHow many times does a man get erect in a day? The average man has 11 erections each day, as well as many more when they are asleep. On average, a healthy man has three to five erections during a full night's sleep.