course hero bio 183 what is the role of egf in regulation of the cell cycle?

by Prof. Litzy Corkery DDS 10 min read

What is the positive and negative regulation of cell cycle?

Regulation of cell cycle: 1 1.Positive regulation of cell cycle:#N#Two groups of proteins; cyclins and cyclin-dependent kinases (Cdks), are... 2 Negative regulation of cell cycle: More ...

What happens at g 0 phase of the cell cycle?

Those cells halt the cycle and attempt to correct the problematic condition, or the cell may undergoes inactivation into G 0 phase and await for further signals when conditions improve. If a cell meets all the requirements for the G 1 checkpoint, the cell will enter S phase and begin DNA replication.

What is the role of the maturation promoting factor in cell cycle?

M check point also involves signal from cyclin dependent kinases. The cell cycle is controlled by regulator molecules that either promote the process or stop it from progressing. i. Maturation promoting factor (MPF):

How is the cell cycle controlled?

The cell cycle is controlled by regulator molecules that either promote the process or stop it from progressing. 1.Positive regulation of cell cycle: Two groups of proteins; cyclins and cyclin-dependent kinases (Cdks), are responsible for promoting the cell cycle

How is EGF regulated?

What is the EGF receptor?

About this website

How is EGF regulated?

The EGF receptor is regulated by several mechanisms: stimulation by ligand binding and self-phosphorylation, inhibition by heterologous phosphorylation and downregulation by ligand. EGF binding stimulates several early events, including phosphatidylinositol (PI) turnover in A431 cells.

What is the EGF receptor?

The EGF receptor is a transmembrane glycoprotein with an external EGF binding domain and a cytoplasmic region that is homologous with other tyrosine kinases . erbB lacks the EGF binding and carboxyl terminal regions, which are thought to be important in regulation.

How is EGF regulated?

The EGF receptor is regulated by several mechanisms: stimulation by ligand binding and self-phosphorylation, inhibition by heterologous phosphorylation and downregulation by ligand. EGF binding stimulates several early events, including phosphatidylinositol (PI) turnover in A431 cells.

What is the EGF receptor?

The EGF receptor is a transmembrane glycoprotein with an external EGF binding domain and a cytoplasmic region that is homologous with other tyrosine kinases . erbB lacks the EGF binding and carboxyl terminal regions, which are thought to be important in regulation.