why do i have to finish the course of antibiotics

by Devin Schoen DDS 4 min read

So why is it that your doctor recommends finishing your course of antibiotics? It's because taking them regularly until the prescription is complete helps ensure that all of the illness-causing bacteria are killed or prevented from multiplying. Even if your symptoms go away, the bacteria may still be present in your body.

If you stop treatment before the antibiotic cycle is over, the remaining bacteria can continue to multiply. If these bacteria become resistant to the antibiotics, they can potentially do even more harm. It may take longer for you to recover from your illness, and your physician may have to prescribe more medication.Oct 2, 2016

Full Answer

Why your doctor tells you to finish all your antibiotics?

You see, there are crucial reasons as to why you are instructed to finish the full course of antibiotics. For one, it's to ensure that all the bacteria that's causing your illness or infection are completely eliminated. Stock photo for illustration purposes only. Image via Dignity Health. Cutting short your prescribed course of antibiotics ...

Should you always finish your full course of antibiotics?

Until now, the advice has always been to finish taking a prescribed course of antibiotics, even if you already feel better (unless a doctor tells you otherwise). Most experts believe that if you stop taking an antibiotic part way through a course, the bacteria you're trying to get rid of can become resistant to the medication.

Why should you always finish your course of antibiotics?

What we can do to help

  • Discover new antibiotics. Firstly, we should keep going the way we have been and continue to discover new agents that are able to destroy bacteria.
  • Only use them when needed. The more we use antibiotics, the greater opportunity bacteria have to see how they work and develop ways to survive their attacks.
  • Use them properly. ...

Why you really should take your full course of antibiotics?

You can help reduce the development of antibiotic resistance if you:

  • Avoid pressuring your doctor to give you an antibiotic prescription. ...
  • Practice good hygiene, to avoid bacterial infections that need antibiotic treatment.
  • Make sure you and your children receive recommended vaccinations. ...
  • Reduce your risk of getting a foodborne bacterial infection. ...
  • Use antibiotics only as prescribed by your doctor. ...

More items...

Why is it important to finish an antibiotic course?

It's important to take the medication as prescribed by your doctor, even if you are feeling better. If treatment stops too soon, and you become sick again, the remaining bacteria may become resistant to the antibiotic that you've taken.

Do you have to finish the whole course of antibiotics?

Traditionally, clinicians and health authorities advocate that patients should complete their full course of antibiotics as prescribed, even when their symptoms have improved, to prevent relapse of infection and the development of antibiotic resistance.

What happens if you stop antibiotics early?

The current recommendation by the World Health Organization (WHO) is to "always complete the full prescription, even if you feel better, because stopping treatment early promotes the growth of drug-resistant bacteria.”

Can I stop taking antibiotics after 5 days?

If you have been fever-free for 24 to 48 hours and are feeling significantly better, “it's reasonable to call your doctor and ask if you can stop your antibiotic,” she says. And be reassured that “stopping short of a full course of antibiotics won't worsen the problem of antibiotic resistance,” Peto says.

Why are antibiotics prescribed for long periods of time?

He suggests traditional long prescriptions for antibiotics were based on the outdated idea that resistance to an antibiotic could develop when a drug was not taken for a lengthy time and an infection was undertreated.

Why is reducing antibiotics important?

The opinion piece, by a team of researchers from across England, argues that reducing the use of antibiotics is essential to help combat the growing problem of antibiotic resistance.

Who said an improvement in symptoms did not necessarily mean the infection had been completely eradicated?

Prof Helen Stokes-Lampard, leader of the Royal College of General Practitioners, said an improvement in symptoms did not necessarily mean the infection had been completely eradicated.

Does the TB antibiotic have rapid resistance?

He accepts there are a few exceptions - for example, giving just one type of antibiotic for TB infections - which is known to lead to rapid resistance.

Is a course of antibiotics random?

She says recommended courses of antibiotics are "not random" but tailored to individual conditions and in many cases courses are quite short.

What are the consequences of discontinuing antibiotics?

Consequences of discontinuing Antibiotics. The unconquerable resilient bacteria are still in our bodies and to make it worse, they no longer need to compete with the population of the weaker bacteria for food for survival.

How long does it take for an antibiotic to kill a middleman?

Any antibiotic dose, in its first couple of days, wipes out the weaklings and weakens the middlemen. Generally, by day 3-4, most of the middlemen are also killed and one starts feeling better as the majority of the bacteria have been defeated.

What are the causes of infection?

There are certain foreign bacteria that have entered our body and are the root cause of the infection. These are the bacteria the prescribed antibiotic intends to identify as foreign intruders and kill without harming our own cells. Source.

Can bacteria survive antibiotics?

These bacteria cells are also more often than not, resistant to the antibiotic now that they have survived mild doses of it. The condition too worsens once the disease relapses and with the bacteria now resistant to the antibiotic, curing the disease becomes all the more difficult.

Why is it important to finish antibiotics?

It is very important that besides recovering fast, you are ensured that the infection in the body part has healed thoroughly. Finishing your antibiotic course is very pertinent even if you are feeling normal as you never know if there are still some bacteria left that might become active again.

Why is it important to complete an antibiotic course?

Your body tends to experience diminished resistance power when attacked by infection causing bacteria. Your body may not be resilient enough to tackle the symptoms and therefore, completing your antibiotic course is important so that you get your sustaining capacity back.

Why do you leave antibiotics half way?

If you leave your antibiotic course half way just because you think you have recovered, then your immunity level won’t improve and you will be highly prone to bacteria and other diseases. So finish your antibiotic course so that your immunity system strengthens.

What happens if you stop taking antibiotics?

Due to this, your recovery will be slow and your resistance power and immunity system will start weakening. You may get re-infected and this time the intensity may be higher.

Why do you need to continue taking antibiotics?

The most important reason why you must continue having your antibiotic dosage as prescribed is that they aid in proper and faster recovery. It is for the recovery from the disease that you have consulted the doctor. If you miss out having your antibiotics, then chances are high that your body will take longer time to heal.

What is the main purpose of antibiotics?

The main task of antibiotics are to attack the harmful bacteria and aid in healing the infection. In the process, antibiotics not only kill the less powerful bacteria but they mostly are effective in eliminating those highly resistant bacteria that may cause the disease again if antibiotics are not taken as per instructions.

How can we cure diseases?

There are different methods for treating these diseases. Some diseases can be cured by providing essential nutrients to the body while there are some kinds of infections that may even need the patient to be hospitalised.

Does stopping antibiotics increase resistance?

The original article bases its findings on a very limited set of clinical trial data for some specific infections. Their main argument is that in the trials they examined, there was no evidence that stopping treatment early increased a patient’s risk of resistant infection. Conclusive? Hardly. Let’s think about the possible microbiological outcomes when you stop taking your antibiotics early.

Can antibiotics cause recurrent infections?

If the latter is true, the persistent population in your body that is causing your recurrent infection could well be resistant to that first set of antibiotics, meaning those antibiotics may well be useless against your infection.

Why are antibiotics important?

They argue that it is not backed by evidence and should be replaced. Antibiotics are important for fighting off infections, but there is a growing global concern about the number of cases in which bacteria have become resistant to these medicines. So that more germs don't build up a resistance to antibiotics, it's important ...

Why do we need to complete the full prescription?

The current recommendation by the World Health Organization (WHO) is to "always complete the full prescription, even if you feel better, because stopping treatment early promotes the growth of drug-resistant bacteria.”. But several experts in infectious diseases are urging policymakers, educators, and doctors to reconsider ...

What did Alexander Fleming say about penicillin?

Alexander Fleming's 1945 Nobel Prize acceptance speech, for example, included his view that if not enough penicillin is given for a streptococcal throat infection, a resistant form of the infection could be passed on to another person. It turned out that the streptococcal bacteria responsible for throat infections have yet to develop a resistance to penicillin.

Can antibiotic resistant bacteria be mutated?

It is true that for certain infections -- such as tuberculosis, gonorrhea, and malaria -- when the germs causing the infection replicate, antibiotic-resistant mutations can happen if not enough antibiotic is given during treatment or only one medicine is used . This is known as targeted selection. But most bacteria do not develop resistance through targeted selection.

Is there evidence that stopping antibiotics early encourages antibiotic resistance?

They say that there is no evidence that stopping antibiotics early encourages antibiotic resistance -- and ...

Does stopping antibiotics early increase resistance?

They say that there is no evidence that stopping antibiotics early encourages antibiotic resistance -- and that taking them for longer than needed makes resistance more likely.

Should antibiotics be stopped when the patient feels better?

They say that in one clinical trial, stopping antibiotics for treat ing pneumonia when the patient's fever went down cut the average length of antibiotic treatment in half and did not affect recovery.

What can you do instead to reduce antibiotic use?

If you’re worried about antibiotic use and resistance, then limiting the need for antibiotics might be a better idea than adjusting your dose when you do need them.

How many people die from antibiotic resistance in the UK?

Antibiotic resistance is certainly becoming a worrying problem these days, with cases of incurable gonorrhoea becoming more and more common and an estimated 700,000 people dying from antibiotic-resistant infections in the UK every year. If the current situation does not improve, this could lead to as many as 10 million deaths per year by 2050, according to a recent UN report. It is therefore important that more research like this is conducted to avoid resistance from developing.#N#The report certainly makes lots of interesting and likely valid points, and it will be interesting to see what further research is conducted into this concept in the future. From a clinical point of view, it is clear that some people recover faster than others and using antibiotics for longer (or more) than is necessary is one of the causes of antibiotic resistance – so there is some logic in this suggestion.#N#It may be that future generations will not be advised to always finish the full course of antibiotics as we have.#N#However, until more research is conducted into this concept, I would recommend following your GP's instructions when it comes to taking antibiotics, and in most cases, this will be to complete the course.

Why is it important to make sure your immune system is in tip top condition?

Making sure your immune system is in tip-top condition is a good way to avoid infections or make it easier to fight them off when they do occur, further reducing the need for antibiotics. Follow my top tips for supporting your immune system:

Why is it important to wash your hands?

Wash your hands! This is especially important when you’re out and about during the winter as bugs can be found everywhere from door handles to keyboards

Can you ask your doctor for antibiotics?

Firstly, don’t ask your GP for antibiotics if you don’t really need them. For colds and flu, for example, antibiotics will not help as these are viral infections. While UTIs, on the other hand, are caused by bacterial infections, it is worth treating mild cases at home before seeing a GP. Of course, for serious infections of any kind it is important to see your GP and follow their treatment advice.

Do antibiotics need more research?

In fact, they also argue that more research is needed to determine what this alternative message could be, and that more research is needed to determine the minimum length of prescription needed for the most common antibiotics.

Is it best to stop treatment when you feel better?

They do suggest ‘patients might be best advised to stop treatment when they feel better, in direct contradiction of WHO advice’. However, the use of the word ‘might’ here is important – this suggestion is merely given as an idea of what message could be given to patients rather than completing the course.

Why do pharmacists help with antibiotics?

As trusted health care professionals, pharmacists are in a unique position to help fight antimicrobial resistance and improve patient safety by dispelling the myth that “more is always better” when it comes to antibiotics. Discussing the benefits of short-course antibiotic therapy with prescribers is an opportunity to improve dialogue about appropriate antibiotic use and provide more optimal care for our patients.

How long should antibiotics be given?

Most clinicians tend to prescribe a fixed duration of antibiotic therapy (e.g., 7, 10, 14 days) for common community-acquired bacterial infections, without taking into account the patient’s clinical response. However, as more data informing duration of therapy accumulate, clinicians are learning that short courses of antibiotics are usually equally effective (in terms of clinical cure and relapse) as longer courses for most common uncomplicated infections treated in the community setting.6Recent clinical trials have challenged the dogma that antibiotic therapy cannot be stopped earlier. Studies show that for community-acquired pneumonia, 5 days are as good as 7 to 107; for pyelonephritis, 7 days are as good as 10 to 148; and for cellulitis, 5 days are as good as 10.9It should be noted, however, that there are some exceptions where longer courses may be preferred: streptococcal pharyngitis10and otitis media in children under 2 years11may require longer courses of treatment, as do deep-seated or chronic infections.12,13Also, there is limited evidence examining duration of treatment for infections occurring in severely immunocompromised patients. Regardless, shorter courses of antibiotics can be safely used for the majority of uncomplicated community-acquired infections.

What does Fleming say about antibiotics?

In his Nobel lecture, Fleming spoke of a hypothetical situation where a person self-treats a sore throat with antibiotics, “He buys some penicillin and gives himself, not enough to kill the streptococci but enough to educate them to resist penicillin.” He advised, “If you use penicillin, use enough.”1Although he was likely alluding to the risks of inadequate dosing, his quote has been construed to mean that inadequate durations of antibiotic therapy breed resistance. This belief, coupled with the underestimated risks of antibiotics and commercial disincentives to use less antibiotics, has shaped modern-day thinking about antibiotics. In fact, “finish the course” is based on 2 ideas about shorter courses of antibiotics that are unsupported by current evidence: 1) they are less effective, and 2) they lead to more resistance.

When discussing antibiotic duration with patients, rather than simply applying a blanket statement, a more tailored approach?

When discussing antibiotic duration with patients, rather than simply applying a blanket statement, a more tailored approach considering the patient, reason for antibiotics and prescribed duration compared to best available evidence is needed. Some experts have suggested counselling the patient to contact his or her prescriber if symptoms have improved prior to completing the course in order to discuss the possibility of an abbreviated course.6As always, patients should be instructed not to share or save antibiotics for later use and to return any unused antibiotics to the pharmacy for disposal.

Can antibiotics cause resistance?

Most of us were taught that terminating antibiotics prematurely can lead to the development of bacterial resistance. This has proven to be a myth as mounting evidence supports the opposite. In fact, it is prolonged exposure to antibiotics that provides the selective pressure to drive antimicrobial resistance; hence, longer courses are more likely to result in the emergence of resistant bacteria.14,15Additionally, long durations of therapy put patients at increased risk for adverse effects,16,17including the development of Clostridium difficileinfection,18which is associated with significant morbidity and mortality.

Is the finish the course message counterproductive?

A recent commentary by Llewelyn et al.19echoes the concept that the “finish the course” message is counterproductive to antibiotic ste wardship. While acknowledging that further research is needed to determine the optimal duration of treatment for many infections, the authors encourage policy makers, educators and physicians to drop the “finish the course” message in favour of emphasizing the harms of antibiotic overuse and a shift towards more patient-centred decision making.

Is it outdated to tell every patient to finish the course of antibiotics?

It is clear that telling every patient to “finish the course of antibiotic therapy , even if you feel better” is outdated. It perpetuates a false belief that shorter courses of antibiotics are harmful and lead to antibiotic resistance. Instead, our focus should shift to ensuring appropriate antibiotic use as well as improving dialogue with prescribers and patients about the harms of antibiotic overuse. The time has come to challenge the maxim “finish the course.” ■

What happens if you don't finish your antibiotics?

Worse, by not finishing, you might contribute to the dangerous rise of antibiotic-resistant bacteria.

How long does it take for an antibiotic to kill a bacteria?

The original theory was this: Treating bacterial infections with an antibiotic kills those bacteria, but this may take a week or more to accomplish. If you stop treatment early, you have only killed the weaker of the bacteria, those bugs most readily wiped out by the antibiotic. The ones leftover are the tougher bacteria, which would have been killed if the treatment continued but now, in the absence of antibiotics, have room to multiply and pass their genetic-based resilience to their progeny. Next time around, the infection is that much tougher.

What are regimens based on?

Regimens are based on clinical studies done when the drugs were first tested, Boucher said. Newer, more refined studies often reveal more effective lengths that strike the balance between killing the bacteria causing an infection and not flooding the environment with more antibiotics.

Do bacteria survive antibiotics?

Bacteria that do survive an onslaught of antibiotics do indeed reproduce quickly and pass along those traits that made them resistant to the antibiotics.

Is completing the course of antibiotics based on scientific evidence?

Boucher said she agrees with the BMJ authors' stance that "completing the course" merely for the sake of lowering the risk of antibacterial resistance is not based on solid scientific evidence. She added, however, that doctors don't often know when a shorter course of antibiotics is as effective as a longer one.

Does it increase antibiotic resistance?

Moreover, having everyone finish their antibiotics all the time may actually be increasing antibiotic resistance worldwide, because it's the taking of antibiotics for longer than absolutely necessary that increases the risk of resistance, Llewelyn said.

What to do if you have leftover antibiotics?

If you wind up with leftover antibiotics, don’t hang on to them . Discard unused antibiotics by returning them to the pharmacy or a community take-back program. Or mix the medication with an unpalatable substance such as coffee grounds or kitty litter, seal it in a bag, and throw it out with the household trash.

How many antibiotics are unnecessary?

About one-third of antibiotics prescribed in doctors’ offices are unnecessary, according to a recent report from the CDC.

How many people get antibiotic resistant infections every year?

Every year, over two million people in the U.S. get infections that are resistant to some types of antibiotics. On the ' Consumer 101 ' TV show, Consumer Reports’ expert Lauren Friedman explains what you need to know about these superbug infections.

Do you need to take all your antibiotics?

The idea that people need to take all their antibiotics, even after they’re feeling better, is based in part on outdated notions about what causes antibiotic resistance, says Lauri Hicks, D.O., a medical epidemiologist at the Centers for Disease Control and Prevention and head of the agency’s Get Smart: Know When Antibiotics Work program.

Can antibiotics cause diarrhea?

Plus, the longer you take antibiotics, the more likely you are to wipe out the “good” bacteria in your intestines, Hicks says. That leaves you vulnerable to infection from the bacterium clostridium difficile, or C. diff, which can cause dangerous inflammation, abdominal cramping, and severe diarrhea, and can even be deadly.

Do you finish the whole bottle of antibiotics?

For decades, doctors and public-health officials have given those who have been prescribed antibiotics the same advice: Finish the whole bottle—even if you’re feeling better. But an analysis published last year in the British Medical Journal challenges that conventional wisdom.

Is shorter therapy better than longer?

Peto notes that “when shorter courses have been compared to longer ones, the shorter therapy has nearly always proved just as effective.”

image