Full Answer
The endometrial tissue contains E, P and androgens and responds to body's cyclic release during cycle. High E causes the tissue to grow while androgens cause them to atrophy. Withdrawal of E and P cause tissue to bleed, causing scarring and adhesion. Endometriosis - The bigger the cyst, the more pain.
Endometrial tissue passes through the fallopian tubes and into the peritoneal cavity and remains responsive to hormones. c. Inflammation of the endometrial tissue develops after recurrent sexually transmitted diseases. d. Endometrial tissue lies dormant in the uterus until the ovaries produce sufficient hormone to stimulate its growth. b.
Laparascopy and histological study Endometriosis - 1st Line Pharmacological treatment - CHC - combined hormonal contraceptives - Suppress ovulation and decrease hormonal levels (ethinyl estradiol in OCP weaker activity than body's own) - Menstrual cycle is shorter, lighter, and more regular
- Progestogenic effects (anti-androgen) and acts by decreasing estrogen production - 1/3 of effect of cyproterone acetate Endometriosis - 3rd line Pharmacological treatment
Retrograde menstruation theory is the oldest principle explaining the aetiology of endometriosis. This theory proposes that endometriosis occurs due to the retrograde flow of sloughed endometrial cells/debris via the fallopian tubes into the pelvic cavity during menstruation [18].
In summary, endometriosis is a protean pathologic entity of uncertain nature and etiology, occurring commonly in the pelvis and rarely in remote sites. The lesions are characterized by gross and microscopic evidence of endometrium, past and present hemorrhage, inflammatory response, scarring, and dense adhesions.
Sampson's theory: Sampson contended that endometriosis arises as the result of retrograde flow of menstrual discharge from the uterus through the fallopian tubes, with spill of endo- metrial cells on to the ovary and other sites in the pelvis.
“Endometriosis occurs when endometrial tissue, the tissue of the inner lining of the uterus, starts to grow outside of the uterus,” says Veerle Bossuyt, MD. The displaced tissue can cause irritation and sometimes severe pain, during menstruation and intercourse. The condition can also lead to infertility.
Endometrial tissue lies dormant in the uterus until the ovaries produce sufficient hormone to stimulate its growth.
Endometrial tissue passes through the fallopian tubes and into the peritoneal cavity and remains responsive to hormones.
Contracting this infection increases the risk of uterine cancer.
Endometriosis - Pathophysiology. Endometrial cells implanting outside the uterus. The endometrial tissue contains E, P and androgens and responds to body's cyclic release during cycle. High E causes the tissue to grow while androgens cause them to atrophy.
Terms in this set (30) Endometriosis - Definition. The presence of endometrial tissue outside the uterus resulting in pelvic pain and infertility. Endometriosis - Endometriosis can present anywhere in the body (True/False) True. However usually limited to pelvic area: ovaries, fallopian tube, bowel, bladder, rectum.
Endometriosis presents in late 20s and early 30s who have delayed pregnancies.
Endometrium shed during menstruation flows back into fallopian tubes and implants in pelvic area.
Aromatase is a key enzyme in production of estrogen and is expressed in endometrial implants.