Gastric and duodenal ulcers are peptic ulcers, which are open sores in the lining of the digestive tract. Gastric ulcers form in the lining of the stomach. Duodenal ulcers develop in the lining of the duodenum, which is the upper part of the small intestine.Aug 23, 2018
Epigastric pain is the most common symptom of both gastric and duodenal ulcers. It is characterized by a gnawing or burning sensation and occurs after meals—classically, shortly after meals with gastric ulcer and 2-3 hours afterward with duodenal ulcer.
Duodenal ulcers are two to three times more common than gastric ulcers. Gastric ulcers are most frequent among those aged 40–70 years, whereas duodenal ulcers are most commonly seen between the age of 25 and 55 years.
Stomach ulcers, also known as gastric ulcers, are sores that develop on the lining of the stomach. You can also get ulcers in part of the intestine just beyond the stomach, which are called duodenal ulcers.
In humans, the most frequent causes of duodenal ulcers are Helicobacter pylori infection, low-dose aspirin treatment, and use of other nonsteroidal antiinflammatory drugs (NSAIDs).
The main cause of this damage is infection with bacteria called Helicobacter pylori, or H. pylori. The bacteria can cause the lining of your duodenum to become inflamed and an ulcer can form. Some medications can also cause a duodenal ulcer, particularly anti-inflammatory drugs such as ibuprofen and aspirin.
Stomach ulcers are usually caused by Helicobacter pylori (H. pylori) bacteria or non-steroidal anti-inflammatory drugs (NSAIDs). These can break down the stomach's defence against the acid it produces to digest food. The stomach lining then becomes damaged causing an ulcer to form.Apr 2, 2021
Gastritis is irritation and inflammation of the stomach lining. This means the lining is red and swollen. It can cause shallow sores in the stomach lining called erosions. An ulcer is a deeper open sore in the lining of the stomach.
Peptic ulcers are open wounds found either in the stomach (gastric ulcers) or the upper part of the small intestine, otherwise known as the duodenum (duodenal ulcers). Peptic ulcers can cause a variety of symptoms, such as pain, discomfort, or gas, though many people do not experience any symptoms at all.Jun 17, 2021
The main symptom caused by a stomach ulcer is having a pain in the upper tummy (abdomen). Other symptoms may include: Bloating. This means your tummy swells because your stomach is full of gas or air.
Here are the top five signs you may have an ulcer:Dull, burning pain. The most common sign of a stomach ulcer is dull, burning pain in the stomach area. ... Indigestion or heartburn. ... Nausea or vomiting. ... Change in stool color. ... Unexplained weight loss.
There are two types of peptic ulcers: gastric ulcers, or ulcers that develop in the stomach lining. duodenal ulcers, or ulcers that develop in the duodenum (small intestine)
Helicobacter pylori, a bacteria, attaches to host cells by adhesins and damages the tissues by releasing toxins. The bacteria thus weakens the abdominal and duodenal mucosal lining and further acts on the mucosa leading to ulcer formation. It also makes i possible for acid to act on the mucosa and cause ulcer formation.
The stomach naturally produces acid which helps in food digestion. People experiencing severe physiological stress such as critically ill patients, their body pH decreases, the abdominal and duodenal environments becomes too acidic. The acid acts on the mucosal lining of both the duodenum and abdomen leading to development of sores.
Complications of perforation are: Pain. The patient presents with sudden severe upper abdominal pain. The pain sometimes radiates to the shoulders and is aggravated by breathing. On palpation the abdomen is extra tender and on auscultation the abdominal sounds are diminished.
NSAIDS in the process of their therapeutic action in the body, inhibits COX-1 reducing prostaglandins secretion. The cytoprotective effect of prostaglandins at the abdominal and duodenal lining is lowered living them susceptible to degradation by acids. The acids act on these linings leading to development of peptic ulcers.