What Is a DNA Palindrome? A palindromic sequence of nucleotides (which are labeled A, T, C, or G) occurs when complementary strands of DNA read the same in both directions, either from the 5-prime end or the 3-prime end.
A palindromic sequence is a nucleic acid sequence on double-stranded DNA or RNA wherein reading 5' to 3' forward on one strand matches the sequence reading backward 5' to 3' on the complementary strand with which it forms a double helix.
Certain DNA sequences have a twofold inverted symmetry and are called self-complementary or palindromic sequences. Palindromic sequences are the usual recognition sites for restriction enzymes and frequently occur as essential elements in regulatory regions.
Mirror-like palindrome – a sequence reads the same forward and backward on a single strand of DNA, as in GTAATG. Inverted repeat palindrome is also a sequence that reads the same forward and backward, but the forward and backward sequences are found in complementary DNA strands.
Solution. A palindromic sequence is a sequence made up of nucleic acids within double helix of DNA and/or RNA that is the same when read from 5' to 3' on one strand and 5' to 3' on the other, complementary, strand. It is also known as a palindrome or an inverted-reverse sequence.
In the reference genome, we found that overall there are a total of 685,064 palindromes in chr 8 and 600,274 in chr 11. On an average, there are 12 palindromes per 3000 bases, but some regions have more than 100 palindromes per 3000 bases.
Palindromes are important sequences within nucleic acids. Often they are the site of binding for specific enzymes (e.g., restriction endobucleases) designed to cut the DNA strands at specific locations (i.e., at palindromes).
What are Palindromes? Words or phases that are the same when read backward or forward. Palindromes are sequences of double-stranded nucleic acids with twofold symmetry.
Palindrome: In genetics, a DNA or RNA sequence that reads the same in both directions. The sites of many restriction enzymes that cut (restrict) DNA are palindromes.
An example of a palindromic sequence is 5'-GGATCC-3', which has a complementary strand, 3'-CCTAGG-5'. This is the sequence where the restriction endonuclease, BamHI, binds to and cleaves at a specific cleavage site.
For a nucleotide sequence to be considered as a palindrome, its complementary strand must read the same in the opposite direction [2]. For example, the sequence 5'-CGATCG-3' is considered a palindrome since its reverse complement 3'-GCTAGC-5' reads the same.
A palindrome is a word, phrase, number, or sequence of words that reads the same backward as forward.