1) An antigen is the substance that elicits an immune response. 2) An epitope is a portion on the surface of an invading particle to which specific antibodies bind. 3) An antibody is a specific immunoglobulin that binds to an antigen. Click card to see definition 👆. Tap card to see definition 👆.
Each immunoglobulin consists of two identical heavy chains and two identical light chains. The variable domain has different tertiary structure in both the heavy and light chains. The different tertiary structure of the variable domain is responsible for the antigen binding specificity. The constant domains are located at the ends ...
Antigenic determinants reside only in the variable region of the light chains. They consist of four polypeptide chains held,... Some are membrane bound. Antigenic determinants reside only in the variable region of the light chains.
1) Charge complementarity occurs when specific noncovalent binding interactions occur between two contacting surfaces. 2) The "charge" interactions can be charge-charge, H-bonding, or van der Waals interactions. 3) Shape complementarity refers to the intimate contact made between an antibody and its target antigen.