Synthetic: Amphetamine and its relative methylphenidate (blocks NT reuptake and enhances release via autoreceptors)
Upper + downer increases the high and potentiates euphoria
Snorted/intranasal - 5-10 mins for onset of action, but longer lasting effects
Compulsive use of a drug, with craving and avoidance of withdrawal
ex. Cocaine tolerance doesn't give sufficient euphoria, increases dose to get a euphoria effect but has not developed tolerance for respiratory depression that may cause death**
Synthetic: Amphetamine and its relative methylphenidate (blocks NT reuptake and enhances release via autoreceptors)
Upper + downer increases the high and potentiates euphoria
Snorted/intranasal - 5-10 mins for onset of action, but longer lasting effects
Compulsive use of a drug, with craving and avoidance of withdrawal
ex. Cocaine tolerance doesn't give sufficient euphoria, increases dose to get a euphoria effect but has not developed tolerance for respiratory depression that may cause death**