Nonsense mutation: (i) changes the codon for an amino acid to a stop codon, leading to termination of translation of the mRNA transcript & a truncated protein. (ii) is exemplified by the mutation which causes βo – thalassemia.
A suppressor mutation is a mutation that occurs at a different site from an original mutation but acts to suppress the original mutation and restore the wild - type phenotype . Suppressor mutations cancel out the effects of a previous mutation . Upload your study docs or become a. Course Hero member to access this document.
three major consequences of point mutation 1. synonymous mutation (silent mutation): no change in codon (no impact on protein) 2. missense mutation (nonsynonymous mutation): codon for one amino acid changed into another 3. Nonsense mutation: codon for one amino acid changed into a stop codon
6. In a missense mutation, the new nucleotide alters the codon so as to produce an altered amino acid in the protein product. With a nonsense mutation, the new nucleotide changes a codon that specified an amino acid to one of the stop codons (TAA, TAG, or TGA).
The codon is the three nucleotide sequence in the mRNA that indicates which amino acid should be incorporated in the growing polypeptide chain. The anticodon is the complementary three nucleotide sequence in the appropriate tRNA. b. Template strand is the DNA strand off which the mRNA is synthesized.
The anticodon is the complementary three nucleotide sequence in the appropriate tRNA. b . Template strand is the DNA strand off which the mRNA is synthesized. The coding, or non-template, strand is the DNA strand complementary to the template strand; it has the same sequence (except for T for U substitutions) as the mRNA. c.
Template strand is the DNA strand off which the mRNA is synthesized. The coding, or non-template, strand is the DNA strand complementary to the template strand; it has the same sequence (except for T for U substitutions) as the mRNA. c.