Immunoglobulin E in Dermatoses Levels in Atopic Dermatitis and Urticaria. From the Department of Dermatology and the Blood Center, University Hospital, Uppsala, Sweden. The serum level of immunoglobulin E (IgE) was found to be significantly greater than normal in a group of 23 out of 28 patients with atopic dermatitis.
Hallmarks of atopic dermatitis include dry, itchy skin and red rashes that come and go. The rashes can occur on any part of the body, although the pattern tends to be different at different ages. In affected infants, the rashes commonly occur on the face, scalp, hands, and feet.
New research supported by the National Institutes of Health delineates how two relatively common variations in a gene called KIF3A are responsible for an impaired skin barrier that allows increased water loss from the skin, promoting the development of atopic dermatitis, commonly known as eczema.Aug 14, 2020
Researchers have identified that mutations in KIF3A, FLG, and CARD11 genes are commonly associated with the development of eczema. Other factors can also cause eczema. For example, environmental triggers such as pollution and tobacco smoke and biological factors such as stress can also result in eczema.Sep 2, 2021