Bipolar disorder is a mental health condition that can cause unusual changes in mood, energy, and behavior. Lithium, anticonvulsants, and antipsychotics are common medications used to treat bipolar disorder.
Full Answer
Medications may include: Mood stabilizers. You'll typically need mood-stabilizing medication to control manic or hypomanic episodes. Examples of mood stabilizers include lithium (Lithobid), valproic acid (Depakene), divalproex sodium (Depakote), carbamazepine (Tegretol, Equetro, others) and lamotrigine (Lamictal).
Lithium and divalproex are first-line mood stabilizers; other options include carbamazepine, oxcarbazepine, and atypical antipsychotics (e.g., aripiprazole, olanzapine, risperidone, quetiapine, and ziprasidone). The above medications can be used as monotherapy for patients with less severe illness.
Caplyta is now FDA-approved for depressive episodes from bipolar I and II. The US Food and Drug Administration (FDA) has approved Caplyta (lumateperone) for the treatment of bipolar depression in adults.
Background. Lithium is considered the gold standard treatment for bipolar disorder (BD). Current clinical guidelines and scientific evidence support its use as a first-line treatment in BD.
Lithium is used to treat mania that is part of bipolar disorder (manic-depressive illness). It is also used on a daily basis to reduce the frequency and severity of manic episodes.
Lithium. Lithium is the first-line choice for preventing mood instability and treating mania. This agent is successful in treating aggressive behavior during acute manic episodes, and it is also the most successful long-term treatment for bipolar disorder.
In the first half of the 20th century, doctors tried treating patients with various types of medications, including barbiturates. Lithium gained research in the 1950s and 1960s and was approved by the FDA for bipolar disorder in the 1970s.
About lithium It's used to treat mood disorders such as: mania (feeling highly excited, overactive or distracted) hypo-mania (similar to mania, but less severe) regular periods of depression, where treatment with other medicines has not worked.
The safest and most efficacious mood stabilizer combinations appear to be the mixtures of anticonvulsants and lithium, particularly valproate plus lithium.
Lithium (Eskalith, Lithobid): This simple metal in pill form is highly effective at controlling mood swings (particularly highs) in bipolar disorder. Lithium has been used for more than 60 years to treat bipolar disorder.
Olanzapine-fluoxetine combo (OFC) (Symbyax) Statistically speaking, OFC may be the most effective therapy for acute bipolar depression, with a number needed to treat (NNT) of 2 compared with 5 to 11 for other FDA-approved atypical antipsychotics.
Drowsiness, dizziness, lightheadedness, nausea, shaking, weight gain, mask-like facial expression, inability to keep still, and agitation may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Your doctor may order another medication to lessen these effects.
Like mentioned, people living with bipolar disorder tend to experience intense emotions — sometimes referred to as mood swings. Manic episodes — a type of euphoric experience — can cause someone to have high amounts of energy, activity, and irritability.
There are several medications used to treat bipolar disorder. In many cases, a combination of medications are used to help people with bipolar disorder.
In short, there’s no one best medication for bipolar disorder. Bipolar disorder is a very variable condition, and the best medication varies by person. Different people may respond better to certain medication combinations than others.
Bipolar disorder is a mental health condition that can cause unusual changes in mood, energy, and behavior. Depending on the severity and type of symptoms someone has, lithium, anticonvulsants, and antipsychotics can be helpful. Although some medications are generally recommended as first-choice options, the true best medication varies by person.