when to allow a fever to run its course

by Clotilde Huel 3 min read

Common Causes

A fever is a common sign of illness, but that's not necessarily a bad thing. In fact, fevers seem to play a key role in fighting infections. So should you treat a fever or let the fever run its course? Here's help making the call.

Related Conditions

Call the doctor if the fever is accompanied by a severe headache, stiff neck, shortness of breath, or other unusual signs or symptoms. 18 years and up. Above 102 F (38.9 C) taken orally. If you're uncomfortable, take acetaminophen (Tylenol, others), ibuprofen (Advil, Motrin IB, others) or aspirin.

Should you treat a fever or let it run its course?

While it took centuries to reach somewhat of a consensus regarding the characterization and definition of fever, unanimity concerning when and if to treat it in critical care patients is still in its infancy. Complicating this matter is both the heterogeneous etiology of fever as well as practice dogma.

When to go to the doctor for a fever?

There are two basic fields of thought: (I) fever should be suppressed because its metabolic costs outweigh its potential physiologic benefit in an already stressed host; vs. (II) fever is a protective adaptive response that should be allowed to run its course under most circumstances.

When and if to treat fever in critical care patients?

Should fever be suppressed or not?

What temperature is considered a fever for COVID-19?

Fever is a common symptom of COVID-19. A body temperature of 100.4 degrees F or higher is generally seen in people with COVID-19, although some people may feel as though they have fever even though their temperature readings are normal.

What is considered a high fever in adults for COVID-19?

A high-grade fever in adults is 103 degrees F or higher.

Can I have COVID-19 if I have fever?

If you have a fever, cough or other symptoms, you might have COVID-19.

Can you run a low-grade fever with COVID-19?

Yes. A fever is one of the common symptoms of COVID-19, but you can be infected with the coronavirus and have a cough or other symptoms with no fever, or a very low-grade one — especially in the first few days.

What are some signs of COVID-19 that need immediate medical attention?

• Trouble breathing• Persistent pain or pressure in the chest• New confusion• Inability to wake or stay awake• Pale, gray, or blue-colored skin, lips, or nail beds, depending on skin tone

What can you take to lower fever when you are infected with COVID-19?

In terms of specifics: acetaminophen (Tylenol), naproxen (Aleve) or ibuprofen (Advil, Motrin) can help lower your fever, assuming you don’t have a health history that should prevent you from using them. It’s usually not necessary to lower a fever – an elevated temperature is meant to help your body fight off the virus.

When do symptoms of the coronavirus disease typically start?

People with COVID-19 have had a wide range of symptoms reported – ranging from mild symptoms to severe illness. Symptoms may appear 2-14 days after exposure to the virus.

Should I take temperature regularly to check for COVID-19?

If you're healthy, you don't need to take your temperature regularly. But you should check it more often if you feel sick or if you think you might have come into contact with an illnesses such as COVID-19.

What are the symptoms of the COVID-19?

Symptoms may appear 2 to 14 days after exposure to the virus.Common symptoms may include: fever or chills; cough; shortness of breath; fatigue; muscle or body aches; headache; new loss of taste or smell; sore throat; congestion or runny nose; nausea or vomiting; diarrhea.

What do I do if I have mild symptoms of COVID-19?

If you have milder symptoms like a fever, shortness of breath, or coughing: Stay home unless you need medical care. If you do need to go in, call your doctor or hospital first for guidance. Tell your doctor about your illness.

How many days can the COVID-19 symptoms last?

How long do COVID symptoms last? Those with a mild case of COVID-19 usually recover in one to two weeks. For severe cases, recovery can take six weeks or more, and for some, there may be lasting symptoms with or without damage to the heart, kidneys, lungs and brain.

What are COVID-19 toes?

Erythema pernio, known as chilblains, have been frequently reported in younger individuals with mild COVID-19 to the extent that they have earned the moniker “COVID toes.” However, the reason behind their development is not yet apparent.

Why are we feverphobic?

Given all of this information, why are we so intent on treating fever? Why are we so fever-phobic? One reason is that we equate fever with illness. We assume that if we lessen fever than we have lessened the degree of illness, when the opposite appears to be true. Another reason is the fear that high fevers can cause brain damage—a concern that hasn’t held up to scientific scrutiny. Yet another reason is the notion that treating fever will prevent febrile seizures, a phenomenon that while frightening, doesn’t cause permanent harm. As it turns out, antipyretics also don’t prevent febrile seizures.

What was the first evidence of fever?

The first evidence that fever was important in people came before Kluger performed his studies in animals. In the early 1900s, before antibiotics to treat bacterial infections were discovered, Wagner von Jauregg injected malaria parasites into the bloodstreams of people with syphilis. The parasites caused high fevers and shaking chills for several days, after which he treated the patients with quinine: an anti-parasitic drug that had been available since the mid-1800s. He found that the high fevers caused by malaria cured syphilis. For this achievement, von Jauregg won the Nobel Prize in 1927. His observations were later extended to include using fever to treat gonorrhea.

Why did Von Jauregg use fever?

His observations were later extended to include using fever to treat gonorrhea. Von Jauregg had shown that fever could be used to treat infections, begging the question of whether reducing fever worsened infections. Many studies have now been performed in children and adults to address this question.

Is fever an adaptive response?

All of these studies proved, as Kluger had postulated, that fever was an adaptive, physiologic, and necessary part of the immune response.

Which cells are more likely to work at higher temperatures?

At higher temperatures, white blood cells (neutrophils ), B cells, and T cells work better. Each of these components of the immune system is important in resolving infections. Neutrophils kill bacteria. B cells make antibodies that neutralize viruses and bacteria. And T cells kill virus-infected cells.

Do fever reducers hurt?

Numerous studies over the past few years have shown that taking fever reducers hurts your body’s ability to recover from an illness.

Who invented fever medicine?

Fever, according to Hippocrates, cooked the raw humor, leading to healing. Then, in 1899, the German company Bayer invented aspirin. Now, suddenly, it became important to treat fever, popularized by the advice, “Take two aspirin and call me in the morning.”

Why should fever be suppressed?

There are two basic fields of thought: (I) fever should be suppressed because its metabolic costs outweigh its potential physiologic benefit in an already stressed host ; vs. (II) fever is a protective adaptive response that should be allowed to run its course under most circumstances. The latter approach, sometime referred to as the “let it ride” philosophy, has been supported by several recent randomized controlled trials like that of Young et al. [2015], which are challenging earlier observational studies and may be pushing the pendulum away from the Pavlovian treatment response.

Who was the first person to describe fever?

The concept of “fever” has been a major focus of medicine for centuries, and while our ability to detect and manage fever has evolved, controversy remains over the best practices with respect to the treatment of this physiologic derangement. Hippocrates, in the 5thcentury BC, was perhaps one of the first to understand and characterize fever as part ...

What is fever in medical terms?

In general, fever is defined as an elevated body temperature above normal variation due to an altered hypothalamic set point. A joint task force from the American College of Critical Care Medicine and the Infectious Diseases Society of America defines fever as a body temperature of 38.3 °C (101 ºF) or higher, which is generally accepted as fever for patients in the ICU setting (4).

How many ICU patients have fever?

While 70% of ICU patients manifest fever, only about 53% are of infectious etiology (5). Despite its source, practitioners often seem to possess an ingrained philosophic opposition towards fever, prompting a knee-jerk response to treat that is not supported by high-level evidence in the ICU population. Suppress it.

Is fever a protective mechanism?

Those in the “let it ride” camp advocate that fever is a protective mechanism with benefits rang ing from enhancing immune-cell function to promoting antimicrobial activity (16,17). In the past decade several studies have supported this hypothesis. A randomized control trial published by our institution in 2005 sought to evaluate the impact of antipyretic therapy on outcomes in critically ill patients (18). Patients were randomized to an aggressive treatment group, consisting of acetaminophen 650 mg every 6 hours for fever >38.5 °C with addition of a cooling blanket for temperature of >39.5 °C, or a permissive group where treatment was initiated at a temperature of >40 °C with acetaminophen and cooling blankets. The study had to be terminated at the interim analysis as there were seven deaths in the aggressive group and only one death in the permissive group. Another randomized controlled trial in critically ill patients without neurotrauma or severe hypoxia also failed to support the treatment of fever showing no significant differences in fever recurrence, infection, antibiotic therapy, ICU and hospital length of stay, or mortality between those receiving external cooling for temperature ≥38.5 °C vs. no antipyretic treatment (19).

Is fever a noxious disease?

In general, two critical assumptions form the basis of the argument for treating fevers, neither of which have been experimentally validated: (I) fever is noxious, and (II) suppression of fever will reduce its noxious effect (6,7). One condition justifying treatment consideration is when a fever’s metabolic cost exceeds its physiologic benefit, but this again, is challenging to quantify (6,8). The only clinical condition with abundant evidence to support aggressive antipyretic treatment is in acute brain injury (9-11). Even the management of febrile seizures in the pediatric population has moved away from antipyretic use as prophylaxis since fever reducing drugs do not reduce seizure recurrence (12,13). Fever reduction via cooling in the ICU setting has been documented in a randomized controlled trial to be of benefit in patients with septic shock leading to a reduction in vasopressor use and mortality (14). Most of the other studies supporting the association of fever with poorer outcomes have been observational in nature (15). In theory, these critically ill patients and those faced with additional physiologic stress may benefit from fever reduction (8), but the evidence on both sides of the argument appears to be mostly equivocal.

Who first described fever as part of the immune system?

Hippocrates, in the 5thcentury BC, was perhaps one of the first to understand and characterize fever as part of the immune response (1). Sydenham described fever as “nature’s engine which she brings into the field to remove her enemy” (2).

Why are people afraid of fever?

The question then arises as to why so many people are afraid of fever. It has been documented that fever phobia is based on unrealistic concerns and misconceptions that have persisted in our culture despite decades of research on the true nature of fever. 14 The perception that body temperature will reach dangerous levels if fever is not treated is unsubstantiated by scientific evidence. On the contrary, the available evidence indicates that body temperature is precisely regulated during fever, and that endogenous antipyretic mechanisms are at work to prevent excessive rises in body temperature. Accordingly, the body temperature of infected patients usually stays around 38.0–39.5℃, rarely reaching 40–41℃ and never exceeding this ceiling. COVID-19 is not an exception in this regard, with fevers of more than 39.0℃ being rare in adults 2 and children. 4 Within this physiological range, the temperature rise per se has never been shown to be harmful to neurons or other cellular phenotypes. In young children, febrile seizure is a concern, but it must be considered that only a very small fraction of the children are predisposed to this condition, that febrile seizures are usually self-limiting and benign, and, what is more, that the pre-emptive use of antipyretic drugs may be ineffective at preventing the seizures. 15

Can you take antipyretics with a fever?

Antipyretic drugs are readily available as over-the-counter medication, being taken routinely by most people at the first sign of a fever. But the symptomatic relief achieved with these drugs comes with the price of putting out a host-defence response that has evolved for millions of years to aid the immune system in the clearance of pathogens. 1 While it may be OK to pay this price in unthreatening infections such as a regular cold or a mild flu, the situation may be different when lives are at stake amid the uncertainty of the COVID-19 pandemic.

Does fever have a cost?

Recognising the value of fever in the fight against infection does not imply that fever has no costs, but the available evidence indicates that the costs of fever outweigh its benefits only at advanced and severe stages of infection, 5 typically when patients are hospitalised because of cardiovascular or respiratory complications. 16, 17 In such states of compromised physiological fitness (sepsis), the energetic cost of fever may be too much for the host to bear and, additionally, fever may heighten the maladaptive inflammation underlying the complications. Interestingly, it often happens that fever is replaced with a self-limiting, spontaneous form of hypothermia in severe sepsis, 18 which, at least in experimental animals, appears to be launched by the host as an alternate defence strategy aimed at tolerating the pathogen while preserving vital bodily functions. 5 This dichotomy in the thermal adaptation of critically ill patients may underlie the controversial results obtained in trials regarding the use of antipyresis in this subset of patients. 16, 19 More refined strategies of patient stratification, perhaps involving temperature trajectories, 20 may help to solve this matter. But regardless of how complex the situation may be with critically ill patients, the situation is unquestionably less complex when an infection such as COVID-19 is at its inception, and competing demands are not at play to offset the value of fever to immunity.

Does fever affect survival?

Animal studies provide substantial support for a role of fever in survival, with it being particularly adaptive in the early, less severe stages of an infection, when the benefits of a raised body temperature to immunity far exceed its costs to the host. 5 Albeit less compelling, clinical evidence is also consistent with this notion. In a prospective trial in trauma patients, an aggressive antipyretic protocol strongly tended to increase the risk of acquiring an infection and developing complications, which prompted interruption of the trial after the first interim analysis of the data. 6 Such a robust effect cannot be undermined. Furthermore, two randomised, double-blind, placebo-controlled trials in rhinovirus-infected volunteers have shown that the use of aspirin, acetaminophen or ibuprofen is associated with increased or prolonged viral shedding. 7, 8 In one of those trials, 7 aspirin and acetaminophen were further shown to suppress the neutralising antibody response and, paradoxically, worsen nasal symptoms. These drugs are not identical with regard to their effects on local inflammation, but have the suppression of fever as a common denominator. And although fever was thought to be occasional in the rhinovirus-infected volunteers, infrequent measures of body temperature (no more than four times a day) are likely to have underestimated the prevalence of low-grade fever in those trials. Indeed, many of the placebo-treated volunteers reported chilliness, 8 a behaviour known to be linked with development of fever.

Making the decision to let a fever run its course can be a wise one in terms of your health

Most of the populace does not know that the body’s immune system works best at 103.5 degrees. However, there is enough of us waking up to the fact that the nature of nature is healing.

Listen to Dr. Lodi explain why its important to let a fever run its course

YouTube When something gets in the way is the only time the body stops healing. When water is prevented from flowing downhill it’s because is something is in the way. Water will always run downhill and as proof, once you eliminate the barrier, it proceeds to flow downhill once again.

What to do if your child has a fever but no symptoms?

If your child has a fever but none of these emergency signs, consider treating at home, seeing your child’s primary healthcare provider or going to a walk-in clinic. Your child may have a viral or bacterial infection that requires treatment but doesn’t need an ER visit.

How long does it take for a child to feel better after a fever?

Most fevers can be cared for at home. With plenty of fluids and rest, they should be feeling better within a few days.

What is the best medicine for a fever in a toddler?

If your child is uncomfortable, you may want to treat the fever with acetaminophen (Tylenol) or ibuprofen (Motrin). Acetaminophen is FDA approved for children 2 months of age and older, and ibuprofen is approved for children 6 months of age and older.

How to take a child's temperature?

The most accurate way to take a child’s temperature is by using a rectal thermometer. But many parents are unsure how to use these so instead use the type of thermometer that swipes across the forehead, also called a “temporal artery thermometer.” These thermometers read heat waves coming from a blood vessel that runs across the forehead just below the skin.

What is a normal temperature for a child?

A normal body temperature is 98.6 F. A temperature of 100.4 F and above is defined as a fever. In general, a temperature of 101 F or lower is a low-grade fever, and a high fever is 102 F or higher. A high fever isn’t indicative of how sick your child is, however. There are some signs to look for to help you decide if it’s time to take your child to the hospital.

Does a fever cause harm?

A fever itself generally does not cause harm and is a sign the body is fighting an infection. Conditions that can cause fever in children:

Is a high fever a serious problem?

A high fever doesn’t always mean there’s a serious problem. It’s important thing to look for other symptoms that accompany the fever to determine if medical attention is required.

What does it mean when you have a fever?

What’s going on when you get a fever? Fever is a sign of inflammation in your body. An inflammatory response can be triggered by infection, such as a flu virus, or by immune-related diseases, cancer, or even drugs and alcohol. Certain chemicals released during inflammation turn your body’s thermostat up past 98 degrees.

Why do we worry about fevers?

We tend to be concerned with fevers because of how disastrous we look and feel with one. It’s more productive for you to stay home and rest, avoiding spreading germs to the rest of the office anyway. If your child has a fever and is lethargic (so sleepy that you can’t wake them) or inconsolable (can’t stop crying), you should take them to a doctor immediately.

What does it mean when your fever breaks?

A fever “breaks” when your body fights off the bug and the inflammation starts calming down. Your thermostat gets reset back to 98 degrees, but your body is still up at 102. Your brain turns on sweating and sends blood near the surface of your skin to release heat, and you cool back down to your normal body temperature.

Why do animals have fevers?

However, fevers show up consistently across species as a response to infection, indicating an evolutionary advantage. Even cold-blooded animals that can’t internally regulate their temperature move to a warm rock when they get sick.

What temperature does the brain need to be to keep the body warm?

Our bodies come with a built-in thermostat in the brain’s hypothalamus. Normally, this thermostat is set to around 98 degrees Fahrenheit. If your body dips below this “set point”—say, from wearing short sleeves during a snowstorm—your brain will turn on processes to create and retain heat. Shivering is the most obvious one; its rapid muscle micro-movements generate heat all over your body.

Why is it bad to have a high temperature?

For example, high temperatures reduce iron levels in the blood, and bacteria have trouble reproducing. Fevers also appear to boost the immune system to fight off infection. So you feel terrible, but you’re actually in a stronger position to beat the bug.

What happens if you get too warm?

On the other hand, if you get too warm, you’ll start sweating. Sweat evaporating off of your skin cools you down. This happens involuntarily, and your brain is really good at keeping your body’s temperature stable.

image