what type of cells does non hodgkin's lymphoma typically start in course hero

by Edna Pfeffer 4 min read

Non-Hodgkin lymphoma (NHL) is generally divided into 2 main types, based on whether it starts in B lymphocytes (B cells) or T lymphocytes (T cells). There are many different types of B-cell lymphomas. Treatment usually depends both on the type of lymphoma and the stage (extent) of the disease, but many other factors can be important as well.

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How is non-Hodgkin lymphoma (NHL) classified?

Non-Hodgkin lymphoma (NHL) is generally divided into 2 main types, based on whether it starts in B lymphocytes (B cells) or T lymphocytes (T cells). There are many different types of B-cell lymphomas. Treatment usually depends both on the type of lymphoma and the stage (extent) of the disease, but many other factors can be important as well.

What are the different types of B cell non Hodgkin lymphoma?

Non-Hodgkin's lymphoma is a group of cancers that start in lymphocytes -- your immune system’s infection-fighting white blood cells. Doctors divide it into types based on the kind of lymphocyte ...

What is Hodgkin lymphoma?

Lymphomas are cancers that start in white blood cells called lymphocytes. There are 2 main types of lymphoma: Hodgkin lymphoma (HL) Non-Hodgkin lymphoma (NHL) HL and NHL come from different types of cells. They behave, spread, and respond to treatment differently, so it's important for you to know which one you have.

What type of lymphocytes are involved in lymphoma?

Dec 06, 2020 · Question 3 What type of cells does non-Hodgkin’s lymphoma typically start in? Answer s: A. red blood cells B. B-cells C. natural killer cells D. T cells Question 4 Which lymphatic system disease has the sign or complication of pathologic fractures associated with it, due to bone weakening?

Diffuse Large B-Cell Lymphoma

Diffuse large B-cell lymphoma (DLBCL) tends to grow quickly. Most often, the treatment is chemotherapy (chemo), usually with a regimen of 4 drugs k...

Small Lymphocytic Lymphoma (and Chronic Lymphocytic Leukemia)

Small lymphocytic lymphoma (SLL) and chronic lymphocytic leukemia (CLL) are considered different versions of the same disease. The main difference...

Extranodal Marginal Zone B-Cell Lymphoma – Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma

Gastric (stomach) MALT lymphoma, the most common type, often occurs as a result of a chronic infection with the bacterium H. pylori, and it often r...

Nodal Marginal Zone B-Cell Lymphoma

This rare type of lymphoma is generally slow growing (indolent), and it often doesn’t need to be treated right away. If it does need treatment, it...

Splenic Marginal Zone B-Cell Lymphoma

This is typically a slow-growing lymphoma. If it is not causing symptoms, it is often watched closely without treating it right away.About 1 in 3 p...

Lymphoplasmacytic Lymphoma (Waldenstrom Macroglobulinemia)

The main treatment for this lymphoma is usually chemo or rituximab. For more detailed information see Treating Waldenstrom Macroglobulinemia.

Primary Central Nervous System (CNS) Lymphoma

This lymphoma begins in the brain or spinal cord. It often develops in older people or those with immune system problems caused by AIDS or drugs gi...

What is the most common type of lymphoma?

Gastric (stomach) MALT lymphoma, the most common type, often occurs as a result of a chronic infection with the bacterium H. pylori, and it often responds to treatment of the infection. Because of this, gastric lymphomas are treated differently from other lymphomas in this group.

Where does lymphoma start?

This lymphoma begins in the brain or spinal cord. It often develops in older people or those with immune system problems caused by AIDS or drugs given to keep transplanted organs from being rejected.

What is the treatment for diffuse large B-cell lymphoma?

Diffuse large B-cell lymphoma (DLBCL) tends to grow quickly. Most often, the treatment is chemotherapy (chemo), usually with a regimen of 4 drugs known as CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone), plus the monoclonal antibody rituximab (Rituxan). This regimen, known as R-CHOP, is most often given in cycles 3 weeks apart.

How many chemo drugs are needed for lymphoma?

It is usually treated in the hospital with intensive chemo, which usually includes at least 5 chemo drugs. Rituximab may also be added. Some examples of chemo regimens used for this lymphoma include:

What is the treatment for follicular lymphoma?

If treatment is needed for follicular lymphoma that is only in 1 lymph node group or in 2 nearby groups that are both above or below the diaphrag m (the thin muscle separating the chest from the abdomen), the preferred treatment is radiation therapy to the lymph node areas affected by lymphoma (called involved site radiation ). Other choices include treatment with chemo plus a monoclonal antibody (rituximab [Rituxan] or obinutuzumab [Gazyva]), or rituximab alone, which might be followed by radiation therapy.

Is lymphocytic leukemia the same as lymphocytic lymphoma?

Small lymphocytic lymphoma (SLL) and chronic lymphocytic leukemia (CLL) are considered different versions of the same disease. The main difference is where the cancer cells are (the blood and bone marrow for CLL, and the lymph nodes and spleen for SLL). CLL and SLL tend to grow slowly, but are very hard to cure.

What is a chemo drug?

The chemo can be a single drug (such as bendamustine) or a combination of drugs, such as the CHOP ( cyclophosphamide, doxorubicin, vin cristine, prednisone) or CVP ( cyclophosphamide, vincristine, prednisone) regimens. If some lymph nodes are very large from the lymphoma, radiation may be used to reduce symptoms.

What are the different types of lymphoma?

Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). CLL and SLL are basically the same disease. Both cancers grow slowly over many years, but sometimes they turn into a faster-growing type. The only difference is where the cancer cells are found: 1 In CLL, lymphocytes are mainly in your blood. 2 In SLL, lymphocytes are mainly in your lymph nodes.

What is peripheral T cell lymphoma?

Peripheral T-cell lymphoma, not otherwise specified: Peripheral T-cell lymphomas are a group of aggressive cancers that start in T cells. The most common one is called “not otherwise specified” because it includes lymphomas that are hard for doctors to put into a single category.

What percentage of lymphoma is cancer?

Only 1% to 2% of lymphomas are this type. In about half of people with lymphoplasmacytic lymphoma, the cancer cells make a protein that makes the blood very thick, a condition called Waldenström macroglobulinemia. Cancer cells are mainly found in bone marrow, but they also can be in your lymph nodes or spleen.

How do you know if you have lymphoma?

Symptoms. As the cancer cells multiply, your lymph nodes swell up. A painless lump in your neck, underarms, or groin is often the first sign that you have non-Hodgkin's lymphoma, but swelling in these glands alone doesn't mean you have cancer. Swollen glands are more often a sign of infection.

What is the best way to diagnose cancer?

MRI, or magnetic resonance imaging. It uses powerful magnets and radio waves to make pictures of organs and structures inside your body. Ultrasound. This uses sound waves to make pictures of the inside of your body. Based on the results of these tests, your doctor will give your cancer a stage.

Is CLL the same as SLL?

Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). CLL and SLL are basically the same disease. Both cancers grow slowly over many years, but sometimes they turn into a faster-growing type. The only difference is where the cancer cells are found: In CLL, lymphocytes are mainly in your blood.

What are the different types of Hodgkin lymphoma?

Classic HL has 4 subtypes: 1 Nodular sclerosis Hodgkin lymphoma or NSCHL: This is the most common type of Hodgkin disease in developed countries. It accounts for about 7 out of 10 cases. It's most common in teens and young adults, but it can occur in people of any age. It tends to start in lymph nodes in the neck or chest. 2 Mixed cellularity Hodgkin lymphoma or MCCHL: This is the second most common type, found in about 4 out 10 cases. It's seen mostly in people with HIV infection. It's also found in children or the elderly . It can start in any lymph node but most often occurs in the upper half of the body. 3 Lymphocyte-rich Hodgkin lymphoma: This sub-type isn't common. It usually occurs in the upper half of the body and is rarely found in more than a few lymph nodes. 4 Lymphocyte-depleted Hodgkin lymphoma: This is a rare form of Hodgkin disease. It's seen mainly in older people and those with HIV infection. It's more aggressive than other types of HL and likely to be advanced when first found. It's most often in lymph nodes in the abdomen (belly) as well as in the spleen, liver, and bone marrow.

Where does Hodgkin lymphoma spread?

Hodgkin lymphoma most often spreads through the lymph vessels from lymph node to lymph node. Rarely, late in the disease, it can invade the bloodstream and spread to other parts of the body, such as the liver, lungs, and/or bone marrow.

What is the name of the cancer that starts in white blood cells?

Lymphomas are cancers that start in white blood cells called lymphocytes. There are 2 main types of lymphoma: Hodgkin lymphoma (HL) Non-Hodgkin lymphoma (NHL) They behave, spread, and respond to treatment differently, so it's important for you to know which one you have. This information is about Hodgkin lymphoma.

What is the most common type of Hodgkin disease?

Nodular sclerosis Hodgkin lymphoma or NSCHL: This is the most common type of Hodgkin disease in developed countries. It accounts for about 7 out of 10 cases. It's most common in teens and young adults, but it can occur in people of any age. It tends to start in lymph nodes in the neck or chest.

What is the name of the cancer cells that look like popcorn?

Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) accounts for about 5% of cases. The cancer cells in NLPHL are large cells called popcorn cells (because they look like popcorn), which are variants of Reed-Sternberg cells. You may also hear these cells called lymphocytic and histiocytic (L&H) cells.

What is the lymph system?

The lymph system is part of the immune system, which helps fight infections and some other diseases. The lymph system also helps control the flow of fluids in the body. The lymph system is made up mainly of cells called lymphocytes, a type of white blood cell. There are 2 main types of lymphocytes:

Where are lymph nodes located?

They're found throughout the body, including inside the chest, abdomen (belly), and pelvis. They're connected to each other by a system of lymphatic vessels.