what is the role of trna synthetase course hero

by Mattie White 10 min read

What is the role of aminoacyl‐tRNA synthetase in protein synthesis?

The aminoacyl‐tRNA synthetase carries out an editing step to ensure against misacylated tRNA being used in protein synthesis. Because the ribosome must treat all aminoacyl‐tRNAs as the same for making the peptide bond, any tRNA bearing the wrong amino acid would be used for protein synthesis,...

What is the function of the enzyme that cleaves the incorrect tRNA?

This function of the enzyme cleaves the incorrect aminoacyl‐ tRNA to yield free amino acid and tRNA. This process is analogous to the editing by the 3′‐5′ exonucleolytic function of DNA polymerases that goes on during DNA synthesis.

What is aminoacylation of tRNA?

Fidelity in tRNA Aminoacylation. Aminoacylation is a two‐step process, catalyzed by a set of enzymes known as aminoacyl‐tRNA synthetases. Twenty aminoacyl‐tRNA synthetases reside in each cell, one per amino acid in the genetic code. In the first step of aminoacyl‐tRNA synthesis, ATP and the appropriate amino acid form an aminoacyl adenylate...

What is the first step of aminoacyl-tRNA synthesis?

In the first step of aminoacyl‐tRNA synthesis, ATP and the appropriate amino acid form an aminoacyl adenylate intermediate. Inorganic pyrophosphate is released and subsequently broken down to free phosphate by the enzyme inorganic pyrophosphatase.

What is the role of tRNA synthetase?

Aminoacyl-tRNA synthetases (ARSs) are generally considered as “housekeepers” involved in protein synthesis, whose primary function is to catalyze the aminoacylation of transfer RNAs (tRNAs).

What is the role of tRNA synthetase quizlet?

What is the function of an aminoacyl-tRNA synthetase? To attach the correct amino acid to its tRNA.

Which of the following is tRNAs role in translation?

transfer RNA / tRNA Transfer ribonucleic acid (tRNA) is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein. tRNAs function at specific sites in the ribosome during translation, which is a process that synthesizes a protein from an mRNA molecule.

What is the function of aminoacyl tRNA synthetases how many different aminoacyl tRNA synthetases are there?

In humans, the 20 different types of aa-tRNA are made by the 20 different aminoacyl-tRNA synthetases, one for each amino acid of the genetic code....Aminoacyl tRNA synthetase.Available protein structures:Pfamstructures / ECODPDBRCSB PDB; PDBe; PDBjPDBsumstructure summary

What is aminoacyl-tRNA synthetase quizlet?

Aminoacyl tRNA synthetases are enzymes that attach a specific amino acid to a specific tRNA molecule.

Which of the following describes the role of aminoacyl-tRNA synthetase?

Which of the following statements best describes the function of aminoacyl tRNA synthetase? Aminoacyl tRNA synthetase catalyzes the charging reaction that links a specific amino acid to a tRNA molecule.

What is the role of tRNA in protein synthesis Brainly?

Role of the t RNA in protein synthesis to decode a codon of mRNA, using its anticodon so as to transfer a specific amino acid to the end of a chain in the ribosome. Thus, forming a protein.

What is the role of tRNA during translation quizlet?

The function of tRNA is to bring the amino acids and place them in the correct potsition to create the desired protein. The ribosomes are made up of rRNA and proteins. There are actually 2 subunits to each ribosome. Their function is to "clamp" the mRNA in place so it's code can be read and translated.

What is the role of tRNA during translation apex?

tRNA is another form of RNA. The 't' stands for 'transfer. ' The role of tRNA during translation is to read the nucleotides on the mRNA strand and then... See full answer below.

Why is the enzyme aminoacyl-tRNA synthetase important to translation and protein synthesis?

Why is the enzyme aminoacyl-tRNA synthetase important to translation and protein synthesis? Ribosomal RNA aids in building the protein from the amino acids that the tRNA attached on the mRNA.

How does tRNA synthetase maintain the translation accuracy?

Aminoacyl-tRNA synthetases play a central role in maintaining accuracy during the translation of the genetic code. To achieve this challenging task they have to discriminate against amino acids that are very closely related not only in structure but also in chemical nature.

What is the function of aminoacyl-tRNA synthesis?

The function of aminoacyl-tRNA synthesis is to precisely match amino acids with tRNAs containing the corresponding anticodon.