Thrombocytes are pieces of very large cells in the bone marrow called megakaryocytes. They help form blood clots to slow or stop bleeding and to help wounds heal.
Thrombocytes (platelets) play an important role in hemostasis, by plugging and repairing damaged blood vessels, thus preventing blood loss. They also participate in a cascade of events that leads to blood clotting by triggering the release of a series of coagulation factors.
Platelets participate in hemostasis in part by their complex interrelationships with coagulation proteins. Several intrinsic platelet proteins are present in alpha-granules (fibrinogen, factor V, factor VIII antigen, platelet factor 4), in the cytosol (factor XIII), or in the membrane fraction (factor XI).
it reduces blood loss across wound. formed elements stay in blood, solutes can seep through plug, platelets contract slighly tighten the plug.
Platelets play a major role in blood clotting. Normally, when one of your blood vessels is injured, you start to bleed. Your platelets will clot (clump together) to plug the hole in the blood vessel and stop the bleeding.
Platelet activation is stimulated by bound platelet secretion products and local prothrombotic factors such as tissue factor. Multiple pathways can lead to platelet activation. There are two principle activating pathways in platelets [5, 6, 9, 11–14].May 26, 2016
Blood-clotting proteins generate thrombin, an enzyme that converts fibrinogen to fibrin, and a reaction that leads to the formation of a fibrin clot.
Platelets are produced from very large bone marrow cells called megakaryocytes. As megakaryocytes develop into giant cells, they undergo a process of fragmentation that results in the release of over 1,000 platelets per megakaryocyte.Jun 4, 2015