Clindamycin Dosage - Usual Adult Dose for Bacterial Infection Oral Serious infection: 150 to 300 mg orally every 6 hours More severe infection: 300 to 450 mg orally every 6 hours Parenteral Serious infection: 600 to 1,200 mg via IV infusion or IM injection per day, in 2 to 4 equally divided doses
Clindamycin: 6 things you should know 1 How it works. Clindamycin is an antibiotic that may be used to treat a wide range... 2 Upsides. Usually reserved for the treatment of serious infections caused by susceptible anaerobic... 3 Downsides. Abdominal pain, pain in the esophagus, nausea, vomiting,... 4 Bottom Line. Clindamycin is an antibiotic...
There are four forms of clindamycin: injectable, intravaginal, oral, and topical. The following table lists forms of clindamycin, along with their dosages in milligrams (mg), milligrams per milliliter (mg/ml), or percentage. How to use and dosage The form and dosage of clindamycin that a doctor prescribes will depend on the infection.
-The concentration of clindamycin in diluent for IV infusion should not exceed 18 mg/mL. IV compatibility: The manufacturer's product information should be consulted; compatibility and duration of stability of drug mixtures varies according to concentration and other conditions.
A course of treatment usually lasts for a week or so, although it will be for longer than this if you are taking clindamycin for a bone infection. If you still feel unwell after finishing the course of treatment, go back to see your doctor.
How much should I take? You'll likely be prescribed a seven-day course of clindamycin for a tooth infection. On each of those seven days, you'll likely need to take a dose every six hours or so.
For the treatment of PCP, the usual dose of clindamycin, when given by mouth, is 300 to 450 mg every 6 hours for 21 days. When given intravenously, the recommended dose is 600 to 900 mg every 6 hours or 900 mg every 8 hours.
Adults and children 13 years of age and older who are pregnant—One applicatorful (100 milligrams [mg]) inserted into the vagina once a day for 7 days, usually at bedtime,. Children younger than 13 years of age—Use and dose must be determined by your doctor.
Clindamycin Overdose If you take too much clindamycin, call your healthcare provider or local Poison Control Center, or seek emergency medical attention right away. If clindamycin is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur.
Official answer. Clindamycin is a strong broad-spectrum antibiotic, typically prescribed for serious infections, such as life-threatening methicillin-resistant Staphylococcus aureus (MRSA) skin infections.
Researchers from the CDC point out that, when antibiotics are deemed necessary for the treatment of acute bacterial sinusitis, the Infectious Diseases Society of America evidence-based clinical practice guidelines recommend 5 to 7 days of therapy for patients with a low risk of antibiotic resistance who have a ...
Serious skin reactions can occur with this medicine. Check with your doctor right away if you have blistering, peeling, or loose skin, red skin lesions, severe acne or skin rash, sores or ulcers on the skin, or fever or chills while you or your child are using this medicine.
While dependent on dosage and severity of the infection, patients can expect their symptoms to improve within 48 hours of taking their first dose of clindamycin. If symptoms don't improve or get worse after that, contact your doctor.
To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you have a "strep'' infection, you should keep using this medicine for at least 10 days.
Clindamycin is used to treat certain types of bacterial infections, including infections of the lungs, skin, blood, female reproductive organs, and internal organs. Clindamycin is in a class of medications called lincomycin antibiotics. It works by slowing or stopping the growth of bacteria.
Clindamycin is a commonly prescribed topical medication to treat acne, and you can usually apply it with minimal side effects. Ideally, you can use it for a short amount of time (about 3 months) in combination with other acne treatments to experience a reduction in your acne's appearance.
There are several antibiotics that kill the common mouth bacteria that cause tooth infections. The best (first-line) antibiotics for tooth infectio...
Clindamycin is a strong broad-spectrum antibiotic, typically prescribed for serious infections, such as life-threatening methicillin-resistant Stap...
Penicillin or amoxicillin are considered the best first-line treatments for Strep throat. According to the CDC (Centers for Disease Control and Pre...
Yes, you can. It is recommended that the use of the antibiotic clindamycin be reserved for patients who are allergic to penicillin or for those pat...
No, clindamycin is not a penicillin antibiotic. Instead, it belongs to a class of medications known as lincomycin antibiotics, or lincosamides. Cli...
Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C difficile. -Because clindamycin therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate.
Usual Adult Dose for Bacterial Infection. -In the treatment of anaerobic infections, parenteral clindamycin should be used initially and then patients changed to oral therapy when clinically appropriate.
US BOXED WARNING (S):#N#-Clostridium difficile associated diarrhea (CDAD) has been reported with the use of nearly all antibacterial agents, including clindamycin and may range in severity from mild diarrhea to fatal colitis. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C difficile.#N#-Because clindamycin therapy has been associated with severe colitis which may end fatally, it should be reserved for serious infections where less toxic antimicrobial agents are inappropriate. It should not be used in patients with nonbacterial infections such as most upper respiratory tract infections.#N#-C difficile produces toxins A and B which contribute to the development of CDAD. Hypertoxin producing strains of C difficile cause increased morbidity and mortality, as these infections can be refractory to antimicrobial therapy and may require colectomy. CDAD must be considered in all patients who present with diarrhea following antibiotic use.#N#-Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents. If CDAD is suspected or confirmed, ongoing antibiotic use not directed against C difficile may need to be discontinued. Appropriate fluid and electrolyte management, protein supplementation, antibiotic treatment of C difficile, and surgical evaluation should be instituted as clinically indicated.#N#Consult WARNINGS section for additional precautions.
for serious infections, 8–16 milligrams per kilogram (mg/kg) per day, divided into three or four equal doses. for more severe infections, 16–20 mg/kg per day, divided into three or four equal doses. For people who have difficulty swallowing, clindamycin comes in granules that a person can dissolve in water.
There are four forms of clindamycin: injectable, intravaginal, oral, and topical. The following table lists forms of clindamycin, along with their dosages in milligrams (mg), milligrams per milliliter (mg/ml), or percentage. Injectable. Intravaginal.
Doctors prescribe clindamycin lotion, gel, and solution to treat acne. A person with acne can apply a thin layer of Cleocin T 1% lotion or clindamycin 1% solution to the affected area of skin twice a day. A person can apply Clindagel 1% once daily to the affected area when acne appears.
Alternatives. Summary. Clindamycin is an antibiotic. It works by stopping bacteria from growing. Doctors prescribe clindamycin to treat bacterial infections, and the drug comes in oral, topical, and injectable forms. Topic al clindamycin is a common treatment for acne and bacterial infections in the vagina.
People use clindamycin to treat bacterial infections. Clindamycin is an antibiotic drug. People use antibiotics to treat bacterial infections. Antibiotics, including clindamycin, do not work for infections caused by viruses. Clindamycin is in the lincosamide family.
The dosages of clindamycin capsules for adults are: for serious infections, 150–300 mg every 6 hours.
Clindamycin capsules may irritate the esophagus, the tube that runs from the mouth to the stomach.
Clindamycin oral is taken by mouth. Clindamycin injection is injected into a muscle, or as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself. Take the capsule with a full glass of water to keep it from irritating your throat.
a metallic taste in your mouth (after clindamycin injection). Common clindamycin side effects may include: nausea, vomiting, stomach pain; mild skin rash; or. vaginal itching or dis charge; This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
The best (first-line) antibiotics for tooth infection include: Amoxicillin, Penicillin, Cephalexin, Clindamycin, Azithromycin. Amoxicillin is often the first choice because it is widely effective and has the fewest gastrointestinal side effects. Continue reading.
You may need frequent medical tests during treatment. If you need surgery, let your surgeon know you use clindamycin as it may interact with certain drugs used for anesthesia. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve.
Before taking this medicine. You should not use this medicine if you are allergic to clindamycin or lincomycin. To make sure clindamycin is safe for you, tell your doctor if you have ever had: colitis, Crohn's disease, or other intestinal disorder; eczema, or allergic skin reaction; liver disease;
Before using clindamycin, tell your doctor if you have kidney disease, liver disease, an intestinal disorder such as colitis or Crohn's disease, or a history of asthma, eczema, or allergic skin reaction. Take clindamycin for the full prescribed length of time.
Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Clindamycin will not treat a viral infection such as the common cold or flu.
For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days .
NADAC is the approximate cost of a medication that pharmacies (not patients) pay for a medication in the United States. Cost data is obtained via monthly surveys of community pharmacies. NADAC pricing is considered a more accurate alternative than average wholesale price (AWP).
Clindamycin is an antibiotic that may be used to treat a wide range of infections including those involving gram-positive and anaerobic bacteria (anaerobic means living without air). Clindamycin works by inhibiting bacterial protein synthesis, which inhibits bacterial growth.
Tell your doctor about any other medications you take, including those brought over the counter from a pharmacy, supermarket, or health store. 6. Response and effectiveness. Peak concentrations are reached within 45 minutes; however, it may take up to 48 hours before infection-related symptoms start to abate. 7.
rifampin. vaccinations, such as BCG and Cholera. Clindamycin is a substrate of CYP3A4 and to a lesser extent, CYP3A5. It is a moderate inhibitor of CYP3A4. Drugs that inhibit CYP3A5=or 3A4 may cause increase blood concentrations of clindomeyin. CYP3A4 or 3A5 may decrease plasma concetrations of clindamycin.
For serious anaerobic infections, the parenteral route is usually used initially but should be switched to the oral route as soon as the patient's condition allows. May be taken with or without food. Generic clindamycin is available. 3. Downsides.
The risk of C. difficile -associated diarrhea may be higher with clindamycin compared with some other antibiotics.
Clindamycin does not treat infections caused by viruses, such as a cold or the flu.
Animal studies do not reveal any evidence of teratogenicity and there is not enough data in humans to make a recommendation. Clindamycin is secreted into breast milk and may potentially cause adverse effects on the GI flora of breast-fed infants.
According to Mayo Clinic, if you miss a dose of clindamycin, take it right away unless you are closer to your next dose. If the latter is true, wait until your next dose. Never double dose.
Significant mortality was observed in mice at an intravenous dose of 855 mg/kg and in rats at an oral or subcutaneous dose of approximately 2618 mg/kg. In the mice, convulsions and depression were observed.
If significant diarrhea occurs during therapy, this antibiotic should be discontinued (see BOXED WARNING ).
Clindamycin hydrochloride capsules, USP are available in the following strengths, colors and sizes:
Clindamycin (clindomycin) is used to treat serious infections caused by certain bacteria in the body. It is not used to treat meningitis.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Recommended dose: Apply a thin film to the affected area (s) 2 times a day Comment: -More than 1 pledget may be used at the same time (e.g., larger surface areas). Use: -Treatment of acne vulgaris
Non-pregnant patients: Vaginal cream: 1 applicatorful intravaginally once at bedtime for 3 consecutive days Vaginal suppository: Insert 1 suppository intravaginally once a day at bedtime for 3 to 7 consecutive days Pregnant patients: -Vaginal cream: 1 applicatorful intravaginally once at bedtime for 7 consecutive days Comment: -A diagnosis of bacterial vaginosis should be confirmed prior to initiating therapy. Uses: -Treatment of bacterial vaginosis in non-pregnant women -Treatment of bacterial vaginosis in non-pregnant women and pregnant women in the second or third trimester.
12 years and older: Recommended dose: Apply a thin film to the affected area (s) 2 times a day Comment: -More than 1 pledget may be used at the same time (e.g., larger surface areas). Use: -Treatment of acne vulgaris
Safety and efficacy have not been established in patients younger than 12 years (topical gel, lotion, pledget, and solution formulations). Vaginal products are not recommended for use in children. Consult WARNINGS section for additional precautions.
Administration advice: -The intravaginal cream formulation is for vulvovaginal use only; not for ophthalmic or oral use. -Pledgets should be used promptly after opening and should only be used once, then properly discarded. -Lotion formulations should be thoroughly shaken immediately prior to use. Storage requirements: -The manufacturer product information should be consulted. General: -Bacterial vaginosis is usually defined by the presence of a homogeneous vaginal discharge with the following: a pH greater than 4.5, 'fishy' amine odor when mixed with 10% KOH solution, and/or the presence of clue cells on microscopic examination. -Diagnosis should be reconfirmed by smears and/or cultures and other pathogens commonly associated with vulvovaginitis ruled out prior to prescribing another course of therapy. -Healthcare providers should consider the potential risk of pseudomembranous colitis associated with this drug; other agents may be more appropriate for use. -If the condition does not improve or worsens during treatment, modification and/or alternative therapy should be considered. Monitoring: -Signs/symptoms of pseudomembranous colitis/Clostridium difficile associated diarrhea (CDAD) Patient advice: -Patients should be instructed to avoid vaginal intercourse or use of other vaginal products (including tampons or douches) during and up to 72 hours after treatment. -Patients should be told to notify their healthcare provider if signs/symptoms of CDAD occur during or after use (e.g., severe diarrhea, abdominal pain). -Patients should be advised that decreases in acne may not occur for 2 to 6 weeks, and some patients may require up to 8 weeks of treatment for definitive beneficial effects..
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
This medication is used to treat a wide variety of bacterial infections.
Status: Discontinued
May Treat: Clostridium perfringens empyema · Staphylococcus aureus osteomyelitis · Staphylococcus aureus skin and skin structure infection · Acne vulgaris · Anaerobic endometritis and more
Alternate Brand Names: Cleocin
Drug Class: Acne Therapy Topical - Anti-infective · Lincosamide Antibiotics · Vaginal Antibacterial - Lincosamides
Availability: Prescription Required
Status: Discontinued
May Treat: Clostridium perfringens empyema · Staphylococcus aureus osteomyelitis · Staphylococcus aureus skin and skin structure infection · Acne vulgaris · Anaerobic endometritis and more
Alternate Brand Names: Cleocin
Drug Class: Acne Therapy Topical - Anti-infective · Lincosamide Antibiotics · Vaginal Antibacterial - Lincosamides
Availability: Prescription Required
Pregnancy: Consult a doctor before using
Lactation: Consult a doctor before using
Alcohol: Limit intake while taking this medication
Driving: May cause drowsiness or dizziness. Use caution