If you have ever taken an antibiotic, you likely know the drill: Finish the entire course of treatment, even if you are feeling better, or else you risk a relapse. Worse, by not finishing, you might contribute to the dangerous rise of antibiotic-resistant bacteria.
“If we don’t complete the course of therapy, there is concern that the bacteria that are left over may be more likely to develop resistance to the antibiotic,” Hicks says. “That turns out to be much less of a problem than was originally believed.”
AS A pharmacist, Allan Wilson should know better if he is suggesting that antibiotic courses are too long. A number of factors will determine how long it takes even an effective antibiotic to eliminate an infection.
If you have ever taken an antibiotic, you likely know the drill: Finish the entire course of treatment, even if you are feeling better, or else you risk a relapse.
If you are taking an antibiotic and can perceive no impact on the infection within 48 hours, you should return to your doctor and request a culture or further investigation. Alan Scott, Lewes, E. Sussex. WHAT about the danger arising from taking more than one may need?
“When you halt treatment early, you allow a small portion of bacteria to remain in your body and that bacteria has the potential to strengthen, change, and develop resistance.” So even if you're feeling better after a few days, that doesn't mean all of the bacteria which made you sick is actually gone yet.
If you forget to take a dose of your antibiotics, take that dose as soon as you remember and then continue to take your course of antibiotics as normal. But if it's almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
When prescribed antibiotics, healthcare professionals advise patients to take the full course of the medication to ensure that the infection is properly treated. Non-adherence to this standard has been thought to have contributed to the rise of antibiotic-resistant superbugs.
If you're all well in three days, stop then. If you're not completely well, take it a little longer. But as soon as you feel fine, stop.
The current recommendation by the World Health Organization (WHO) is to "always complete the full prescription, even if you feel better, because stopping treatment early promotes the growth of drug-resistant bacteria.”
Researchers from the CDC point out that, when antibiotics are deemed necessary for the treatment of acute bacterial sinusitis, the Infectious Diseases Society of America evidence-based clinical practice guidelines recommend 5 to 7 days of therapy for patients with a low risk of antibiotic resistance who have a ...
The evidence supporting shorter courses is especially strong for community-acquired pneumonia. At least 12 randomized controlled trials in adults have shown that three to five days of antibiotics works as well as five to 14 days, and a 2021 study found the same holds true for children.
A growing body of research finds that telling patients to finish a full course of antibiotics even if they're already feeling better not only fails to prevent drug-resistant “superbugs” from forming, but also might make those pathogens stronger.
If you have been fever-free for 24 to 48 hours and are feeling significantly better, “it's reasonable to call your doctor and ask if you can stop your antibiotic,” she says. And be reassured that “stopping short of a full course of antibiotics won't worsen the problem of antibiotic resistance,” Peto says.
Traditionally, clinicians and health authorities advocate that patients should complete their full course of antibiotics as prescribed, even when their symptoms have improved, to prevent relapse of infection and the development of antibiotic resistance.
The standard practice is to give antibiotics for 10 days. A recent clinical trial tried stopping antibiotics after 5 days, and found it less effective than the standard 10 days. They also observed no difference in drug resistance among harmless bacteria residing in the throat.
These include the fact that there are areas of the body where antibiotics do not achieve good penetration (e.g. the lungs and sinuses). The quantity of infective material that may have built up in the body, and from which re-infection may occur, must also be taken into account.
If the drug manufacturers know the antibiotic is effective in 48 hours then a recommended five-day treatment would keep everybody happy, including their shareholders. Allan Wilson, Pharmacist, Comrie, Perthshire. AS A pharmacist, Allan Wilson should know better if he is suggesting that antibiotic courses are too long.
THE danger to the individual is that the infection will recur, and will be more difficult to treat when it does. The danger to the rest of us is that the general population of the infecting bacterium will become more resistant to the antibiotic concerned.
This debate is meaningless in light of the fact that decision to go to a doctor was that of the patient and he/she decided to go because of the confidence in the doctor's ability. Once prescribed by the doctor, I strongly believe that one must complete the course as prescribed.
As the surviving bacteria reproduce, the resulting infection would not be treatable with the same antibiotic. If the infection is passed on to someone else, their infection will also be resistant to the antibiotic. Jim Lodge, London SE4.
Antibiotics will not cure viral infections. So, prescribing antibiotics without properly ascertaining the cause of infection is indeed an equally real danger.
Mary Ingham, Ramsgate, Kent. I think the danger of creating antibiotic-resistant bacteria is very real. Bacterial infections, before antibiotics, quite often proved to be fatal and by discontinuing a course of prescribed antibiotics, we run the risk of going back there.
The current recommendation by the World Health Organization (WHO) is to "always complete the full prescription, even if you feel better, because stopping treatment early promotes the growth of drug-resistant bacteria.”. But several experts in infectious diseases are urging policymakers, educators, and doctors to reconsider ...
They argue that it is not backed by evidence and should be replaced. Antibiotics are important for fighting off infections, but there is a growing global concern about the number of cases in which bacteria have become resistant to these medicines. So that more germs don't build up a resistance to antibiotics, it's important ...
They say that there is no evidence that stopping antibiotics early encourages antibiotic resistance -- and ...
By cutting treatment short, you increase the chances of the existing bacteria mutating and becoming resistant, therefore making it harder to treat the next time around.
According to the World Health Organisation, stopping treatment early involves the risk of not getting all of the bacteria that made you unwell killed off. As we don’t know who can safely stop treatment early, making your own judgement could result in you falling ill again.
In pneumonias that were acquired in the hospital, for example, randomized-controlled trial data indicates that short-term medication courses — for three to five days — is as effective as longer courses and were associated with lower rates of infection recurrence and antibiotic resistance.
In other words, if a child feels completely better after five or six days out of a 10-day course, it's safe to stop.
Take your antibiotic, all of it, doctors order. Five out of every six Americans are prescribed antibiotics each year, according to the Centers for Disease Control and Prevention.
According to the report, an individual’s risk of resistant infection depends on how much of an antibiotic they've taken in the past, so reducing exposure with shorter courses of antibiotic treatment is associated with lowered risk of resistant infection. Patients are put an unnecessary risk from antibiotic resistance when treatment is given ...
Patients are put an unnecessary risk from antibiotic resistance when treatment is given for longer than necessary, not when it is stopped early, British researchers say. Shutterstock. "It very much is challenging the dogma that shorter courses of antibiotics are inferior.
Doctors are still figuring out what the appropriate length of treatment is, Schaffner said. Antibiotics are vital to modern medicine but overuse has contributed to antibiotic resistance, now considered a global threat to human health.
Worse, by not finishing, you might contribute to the dangerous rise of antibiotic-resistant bacteria. The advice to always finish your antibiotics has long been considered medical dogma, and can be seen today on the websites of the World Health Organization, the U.S. Food and Drug Administration and other leading health authorities.
The idea that stopping an antibiotic treatment early encourages antibiotic resistance is not supported by scientific evidence, he said. Moreover, having everyone finish their antibiotics all the time may actually be increasing antibiotic resistance worldwide, because it's the taking of antibiotics for longer than absolutely necessary ...
Boucher said she agrees with the BMJ authors' stance that "completing the course" merely for the sake of lowering the risk of antibacterial resistance is not based on solid scientific evidence. She added, however, that doctors don't often know when a shorter course of antibiotics is as effective as a longer one.
If you wind up with leftover antibiotics, don’t hang on to them . Discard unused antibiotics by returning them to the pharmacy or a community take-back program. Or mix the medication with an unpalatable substance such as coffee grounds or kitty litter, seal it in a bag, and throw it out with the household trash.
If you have been fever-free for 24 to 48 hours and are feeling significantly better, “it’s reasonable to call your doctor and ask if you can stop your antibiotic,” she says. And be reassured that “stopping short of a full course of antibiotics won’t worsen the problem of antibiotic resistance,” Peto says.
The idea that people need to take all their antibiotics, even after they’re feeling better, is based in part on outdated notions about what causes antibiotic resistance, says Lauri Hicks, D.O., a medical epidemiologist at the Centers for Disease Control and Prevention and head of the agency’s Get Smart: Know When Antibiotics Work program.
Plus, the longer you take antibiotics, the more likely you are to wipe out the “good” bacteria in your intestines, Hicks says. That leaves you vulnerable to infection from the bacterium clostridium difficile, or C. diff, which can cause dangerous inflammation, abdominal cramping, and severe diarrhea, and can even be deadly.
Talk to Your Doctor About Antibiotics. About one-third of antibiotics prescribed in doctors’ offices are unnecessary, according to a recent report from the CDC. Doctors commonly prescribe these drugs for upper-respiratory illnesses such as bronchitis, colds, and the flu.
In those cases, it's usually important to finish all the medication prescribed for you. However, for less serious illnesses, such as pneumonia, a sinus infection, or a urinary tract infection, you may not need to finish, Hicks says.
According to Hicks, scientists have come to realize that the larger problem is that antibiotics affect not only the bacteria causing the infection but also the trillions of other bacteria that live in and on your body. “We have more bacteria in our body than human cells,” she says.
In other words, when you stop taking antibiotics before the course is over, the infection can morph into something stronger that is resistant to the originally prescribed antibiotics.
1. Starting a Second Round After the Course Is Over. This is where you may feel the symptoms of a disease/ailment recurring even after the whole course of the treatment is over.
Starting Antibiotics After Stopping the Course Causes Antibiotic Resistance. Usually, whenever a doctor prescribes an antibiotic course, it’s because the doctor suspects an infection in the body. So the antibiotic course prescribed will be aimed at destroying all the bacteria that are causing the infection.
An antibiotic course is also prescribed to prevent a recurring infection from coming – an infection that could potentially be stronger or more severe than the first infection. If you stop taking antibiotics due to symptoms subsiding, then decide to take them again, your system could become resistant to antibiotics.
A person going through bronchitis or pneumonia may have taken a one-week course of antibiotics and have completed it. This one-week course is prescribed to destroy all the bacteria of the disease. However, after this course is over, you may develop similar symptoms of the disease like coughing.
In other words, the time between stopping and restarting gives the bacteria in the body time to learn how to survive when the same antibiotics are taken again. In these types of cases, doctors will recommend a stronger antibiotic.
First-round antibiotic treatments are usually given for 7-10 days. When the first-round treatments are given for a specific infection, many feel relief from pain within the 24-48 hours after taking the medication. If they then decide to stop the antibiotic at this point, the bacteria that was dying when taking the antibiotics can start ...