Federal animal welfare regulations (CFR Ch.1, 2.36 (b) (5-7) require that USDA-registered research facilities report an annual census of regulated animals used in research and teaching, the species used, and the number of animals placed in each of the four “Categories of Pain and Distress” (B,C, D and E).
Full Answer
Engaging in appropriate monitoring, interventions, and implementation of humane endpoints. How do federal regulations address animal pain and distress in research? Animal pain and distress must be avoided or minimized when consistent with sound scientific practices.
Write Spell Test PLAY Match Gravity Created by katekate1517 Terms in this set (60) How is "pain and distress" defined in regard to laboratory animal research? Pain - an unpleasant sensation and emotional experience. Distress - a state in which an animal is unable to adapt to one or more stressors.
Animal pain and distress must be avoided or minimized when consistent with sound scientific practices. Which of the following factors may cause or contribute to animal pain and distress related to a research procedure? surgical wounds hypothermia dehydration all of the above all of the above
animal pain and distress should be eliminated at all costs animal pain and distress may introduce sources of nonexperimental variation into a study animal pain and distress alleviation is not relevant for disease states
Animal use activities that involve accompanying pain or distress to the animals and for which appropriate anesthetics, analgesics, tranquilizing drugs and/or humane endpoints are used to avoid pain, distress or discomfort.
Animal use activities that involve accompanying pain or distress to the animals and for which appropriate anesthetic, analgesic, tranquilizing drugs or other methods for relieving pain or distress are not used. Category E procedures require strong scientific justification as to why pain-relieving drugs or other methods for relieving pain cannot be used. This includes citation (s) to published studies if applicable — describing the alternatives that were considered and how alternatives will be used whenever possible, clarifying whether animals will be euthanized when moribund, and if not, what information is to be gained in the interval between moribundity and death.
Chemical immobilization or restraint, such as for transport or for procedures that are not considered painful but restraint is required for the species to perform the procedure correctly. Studies involving clinical signs not judged to involve more than slight pain or distress.
You are not required to include nonresearch-related veterinary care in determining the category of use. Please note that the severity or duration of the pain or distress and/or the use of anesthesia or analgesia to alleviate pain or distress may result in animals being placed in different categories.