explain how glucagon changed plasma glucose concentration over the course of the experiment.

by Amparo O'Conner 8 min read

Once glucose levels increase above normal, the elevated blood plasma glucose levels inhibit secretion of glucagon. the insulin/glucagon ratio changed over the course of the experiment indicating changes in glucose storage and changes in ability to inrease blood glubose concentration via glycogenolysis and glucaneogenesis.

Full Answer

How did the insulin/glucagon ratio change over the course of the experiment?

the insulin/glucagon ratio changed over the course of the experiment indicating changes in glucose storage and changes in ability to inrease blood glubose concentration via glycogenolysis and glucaneogenesis. State when glucose storage capability was highest and why

What kept the plasma glucose constant during the experiment?

Glucagon kept plasma glucose constant Explain what caused the change in plasma ketone concentration over the course of the experiment Fasting increased the use of fats as energy thereby creating ketone bodies Explain how negative feedback caused the changes in plasma insulin concentration observed

How do glucose levels affect glucagon secretion?

Decreasing blood plasma glucose levels stimulate secretion of glucagon which increases glucose levels. Once glucose levels increase above normal, the elevated blood plasma glucose levels inhibit secretion of glucagon.

How does insulin change plasma glucose concentration?

Explain how insulin changed plasma glucose concentration over the course of the experiment. Insulin increases the transport of glucose into body cells causing blood glucose levels to decrease. When the insulin calmed down a bit and decreased that when a rise in glucose was presented. 2.

How does glucagon change plasma glucose concentration?

How glucagon works. Glucagon works to counterbalance the actions of insulin. About four to six hours after you eat, the glucose levels in your blood decrease, triggering your pancreas to produce glucagon. This hormone signals your liver and muscle cells to change the stored glycogen back into glucose.

How insulin changed plasma glucose concentration over the course of the experiment?

Explain how insulin changed plasma glucose concentration over the course of the experiment. Insulin changed the plasma glucose because after a meal the amount of insulin secreted into the blood will increase and that caused the plasma glucose to rise.

When was plasma insulin glucagon concentration highest?

Plasma insulin/glucagon concentration differed significantly. Insulin levels were at their highest during 1 hour post meal time exceeding 180 while glucagon was it its highest during the 2 hour at 36.

What happens when plasma glucose concentration increases?

It is important that the concentration of glucose in the blood is maintained at a constant level and controlled carefully. Insulin is a hormone - produced by the pancreas - that regulates glucose concentrations in the blood....Action of insulin.Low glucoseHigh glucoseEffect on blood glucose levelIncreasesDecreases2 more rows

Does glucagon increase blood glucose levels?

Glucagon is a glucoregulatory peptide hormone that counteracts the actions of insulin by stimulating hepatic glucose production and thereby increases blood glucose levels.

How is blood glucose level regulated by glucagon and insulin?

When blood glucose falls, cells in the pancreas secrete glucagon. Glucagon instructs the liver to convert glycogen to glucose, making glucose more available in the bloodstream. From there, insulin attaches to its receptors on the body's cells and ensures that they can absorb glucose.

What is the concentration of glucose in plasma?

Normal plasma glucose levels are defined as under 100 mg/dL during fasting and less than 140 mg/dL 2-hours postprandial. Additionally, glucose levels in healthy individuals can vary with age.

How do you measure plasma glucose concentration?

The level of glucose in the blood can be measured by applying a drop of blood to a chemically treated, disposable 'test-strip', which is then inserted into an electronic blood glucose meter. The reaction between the test strip and the blood is detected by the meter and displayed in units of mg/dL or mmol/L.

How does Glycogenolysis break down glycogen into glucose?

Glycogenolysis breaks down glycogen into glucose. Specifically, the process of glycogenolysis forms one molecule of glucose-6-phosphate, leaving the remaining chain of glycogen with one less molecule of glucose. This process is repeated many times so that multiple glucose molecules can be removed from the chain.

Why does the concentration of glucose in the blood increase?

The concentration of glucose in the blood plasma is increased when (carbohydrate-containing) food is eaten and digested, and the body needs to convert surplus glucose into other compounds which it can store.

What is the relationship between plasma glucose concentration and reabsorption rate of glucose?

Renal glucose reabsorption tends to increase with plasma glucose levels, up to plasma concentrations of 180 mg/dL to 200 mg/dL. Among patients with diabetes, an excess of approximately 13 grams of glucose is taken up from the systemic circulation, of which 85% is attributed to increased renal glucose uptake.

What is released when the concentration of glucose drops in the blood?

When blood glucose levels drop, such as after an overnight fast, the pancreas releases a hormone called glucagon. Glucagon binds a GPCR on liver and muscle cells called the glucagon receptor, which then stimulates the cells to release glucose into the bloodstream.

Why does the pancreas produce insulin?

The high concentration of glucose in the blood causes the pancreas to produce insulin which helps the blood glucose levels return to normal. Once the blood sugar level is stabilized, negative feedback inhibits the pancreas from producing insulin, thus maintaining homeostasis.

How does a high blood ketone level help the body conserve blood glucose?

(1 mark) A high blood ketone level helps the body conserve blood glucose because ketones can be used to make ATP instead of glucose from the blood. The symptoms of diabetes mellitus include high plasma glucose levels.

Why is my blood glucose high?

Explain how diabetes causes this symptom. ( mark) Diabetes mellitus causes high plasma glucose levels because the body does not produce enough insulin. Insulin helps your body convert glucose from the blood into energy.

Does glucagon increase blood glucose?

Glucagon increased the plasma glucose concentration over the course of the experiment. After eating a meal, the blood glucose levels increased, causing an imbalance. The high concentration of glucose in the blood causes the pancreas to produce insulin which helps the blood glucose levels return to normal.

Why is glycogenolysis important?

glycogenolysis to maintain blood plasma glucose levels. Blood plasma ketone levels are highest immediately before the meal when carbohydrate fuels are not available. High ketone levels indicates that the body is using fatty acids to make ATP instead of glucose in the blood. Once absorption of nutrients from the meal is complete ...

What does a high insulin/glucagon ratio mean?

A high insulin/glucagon ratio, as observed 1 and 2 hr post meal, indicates increased storage of glucose. maintaining blood plasma glucose levels. Ketones can be used as a fuel for cells to produce ATP. When plasma glucose is low then ketones can be used in addition to glucose, thereby sparing blood glucose.

How does insulin affect glucose levels?

Insulin reduces blood plasma glucose by stimulating transport of glucose into cells. Insulin caused glucose levels to decrease 2 and 3 hr post meal. explain how glucagon changed plasma glucose concentration over the course of the experiment.

How long after a meal will glucose levels be highest?

plasma glucose levels will be highest. 1- 3 hours after the meal. plasma ketone levels will be highest. before the meal (fasting) plasma insulin levels will be highest. 1-3 hours after the meal. plasma glucagon levels will be highest.

Why is it important for glucose to not enter the cell?

If glucose cannot enter cells, cells cannot use glucose to make ATP and fatty acids are broken down to make ATP. Breakdown of fatty acids results in production of ketones. Buildup of ketones causes ketoacidosis.

What happens when blood glucose levels drop below normal?

Once absorption of nutrients from the meal is complete and blood plasma glucose levels fall below normal range, the body uses stored glucose and fatty acids to make ATP. Increasing blood plasma glucose levels stimulate secretion of insulin which decreases glucose levels.

What hormones stimulate glycogenolysis?

Epinephrine and norepinephrine stimulate glycogenolysis and lipolysis (breakdown of triglycerides to fatty acids and glycerol). Glycogenolysis increases blood plasma glucose levels by breaking down glycogen and releasing glucose molecules. Lipolysis provides fatty acids that can be used to make ATP.

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