In men, LH stimulates testosterone production from the interstitial cells of the testes (Leydig cells). FSH stimulates testicular growth and enhances the production of an androgen-binding protein by the Sertoli cells, which are a component of the testicular tubule necessary for sustaining the maturing sperm cell.
Gonadotropin-releasing hormone (GnRH) is a releasing hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is a tropic peptide hormone synthesized and released from GnRH neurons within the hypothalamus.
In the male, FSH and LH stimulate Sertoli cells and interstitial cells of Leydig in the testes to facilitate sperm production. The Leydig cells produce testosterone, which also is responsible for the secondary sexual characteristics of males.
The principle regulator of LH and FSH secretion is gonadotropin-releasing hormone (GnRH, also known as LH-releasing hormone). GnRH is a ten amino acid peptide that is synthesized and secreted from hypothalamic neurons and binds to receptors on gonadotrophs.
1.2. Generally, females and males have the same hormones (i.e., estrogens, progesterone, and testosterone), but their production sites, their blood concentrations, and their interactions with different organs, systems, and apparatus are different [29].
What is the function of GnRH in females? In the female reproductive system, GnRH indirectly stimulates your body's production of estrogen and progesterone. These are the predominant female sex hormones that play a key role in ovulation and conception (your ability to get pregnant).
LHIn men, LH primarily stimulates testosterone production, while FSH stimulates the production of sperm. The testes must be capable of response to this hormonal stimulus.
LH levels quickly rise just before ovulation. In men, LH causes the testicles to make testosterone, which is important for producing sperm.
LH stimulates Leydig cell T production, and FSH stimulates in Sertoli cells, in synergy with T, the production of regulatory molecules and nutrients needed for the maintenance of spermatogenesis. Hence, both T and FSH regulate spermatogenesis indirectly through Sertoli cells.
Follicle stimulating hormone (FSH) is a hormone released by the pituitary gland in the brain. In men, it stimulates testicular growth and helps produce a protein that plays a vital role in male fertility by aiding in the creation of normal sperm cells and maintaining them until they are ready to be released.
Luteinizing hormone in men or DMAB LH stimulates your testes to make testosterone, a hormone your body needs to produce sperm. Testosterone is also responsible for secondary sex characteristics, like a deeper voice and more body hair and muscle mass.
testesTestosterone is produced by the gonads (by the Leydig cells in testes in men and by the ovaries in women), although small quantities are also produced by the adrenal glands in both sexes. It is an androgen, meaning that it stimulates the development of male characteristics.