course hero 5. explain the molecular clock and how it is used.\

by Toy Hegmann DVM 4 min read

What is a molecular clock and how is it used?

The molecular clock is a figurative term for a technique that uses the mutation rate of biomolecules to deduce the time in prehistory when two or more life forms diverged. The biomolecular data used for such calculations are usually nucleotide sequences for DNA, RNA, or amino acid sequences for proteins.

What is a molecular clock and how are they used in phylogenetic analysis?

The molecular clock posits a constant rate of genetic change among lineages, such that estimates of rates can be extrapolated across the Tree of Life to infer the timing of evolutionary divergence events. For this reason, the molecular clock has become a valuable component of phylogenetic analysis.

What is a molecular clock in simple terms?

: a measure of evolutionary change over time at the molecular level that is based on the theory that specific DNA sequences or the proteins they encode spontaneously mutate at constant rates and that is used chiefly for estimating how long ago two related organisms diverged from a common ancestor.

What is a molecular clock example?

For example,the gene that codes for the protein alpha-globin (a component of hemoglobin) experiences base changes at a rate of . 56 changes per base pair per billion years1. If this rate is reliable, the gene could be used as a molecular clock.

What is a molecular clock in phylogenetic tree?

Molecular clocks enable the time of divergence of ancestral sequences to be estimated. When we carry out a phylogenetic analysis our primary objective is to infer the pattern of the evolutionary relationships between the DNA sequences that are being compared.

What is the basis for the use of a molecular clock?

Molecular clocks are helpful by showing the linear relationship between the genetic distance and time since a species has diverged from another, which usually dates back further than the fossil record.

What is meant by the term molecular clock How is this concept related to the neutral theory of evolution?

From the standpoint of the neutral theory of molecular evolution, it is expected that a universally valid and exact molecular evolutionary clock would exist if, for a given molecule, the mutation rate for neutral alleles per year were exactly equal among all organisms at all times.

How is molecular clock calculate?

Measuring the age of a species with the molecular clock technique requires just two simple things: an estimate of the number of genetic mutations between a species and its closest relative and the average genetic mutation rate (i.e., how many mutations show up in a population in a specified time frame, such as 5 ...

How does molecular clock contribute as a new evidence of evolution?

Molecular clocks are used to determine how closely two species are related by calculating the number of differences between the species' DNA sequences or amino acid sequences. Molecular evidence for evolution includes that all living things share the same biochemical building blocks.

Why is the use of a molecular clock controversial?

Molecular clocks in general are much more "erratic" than previously thought, and practically useless to keep accurate evolutionary time, the researchers conclude. They attribute this to the vagaries of natural selection, which may at times constrain specific genetic mutations in certain lineages.

How does a molecular clock measure time quizlet?

A molecular clock is a measure of evolutionary time based on the theory that specific DNA sequences mutate at constant rates. To use a molecular clock, scientists first select two different species and compare their DNA sequences.

Which did the molecular clock data show?

Which did the molecular clock data show? Clams and squid have been evolving separately for a shorter time than clams and snails.